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2026-08-18T18:23:34Z
User contributions
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https://blackwiki.org/index.php?title=Template:Glutamate_receptor_modulators&diff=5492805
Template:Glutamate receptor modulators
2016-03-26T02:25:43Z
<p>74.87.207.3: </p>
<hr />
<div>{{Navbox<br />
| name = Glutamatergics<br />
| title = [[Glutamate]]rgics<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
| listclass = hlist<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Receptor (biochemistry)|Receptor]]<br />{{smaller|([[Ligand (biochemistry)|ligands]])}}<br />
| list1 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[AMPA receptor|AMPA]]<br />
| list1 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Fluorowillardiine]]<br />
* [[Acromelic acid|Acromelic acid (acromelate)]]<br />
* [[AMPA]]<br />
* [[β-N-Oxalylamino-L-Alanine|BOAA]]<br />
* [[Domoic acid]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Proline]]<br />
* [[Quisqualic acid]]<br />
* [[Willardiine]]; ''Positive allosteric modulators:'' [[Aniracetam]]<br />
* [[Cyclothiazide]]<br />
* [[CX-516]]<br />
* [[CX-546]]<br />
* [[CX-614]]<br />
* [[Farampator|Farampator (CX-691, Org 24448)]]<br />
* [[CX-717]]<br />
* [[CX-1739]]<br />
* [[CX-1942]]<br />
* [[Diazoxide]]<br />
* [[Hydrochlorothiazide|Hydrochlorothiazide (HCTZ)]]<br />
* [[IDRA-21]]<br />
* [[LY-392,098]]<br />
* [[LY-404,187]]<br />
* [[LY-451,646]]<br />
* [[LY-503,430]]<br />
* [[Mibampator|Mibampator (LY-451,395)]]<br />
* [[Org 26576]]<br />
* [[Oxiracetam]]<br />
* [[PEPA (drug)|PEPA]]<br />
* [[PF-04958242]]<br />
* [[Piracetam]]<br />
* [[Pramiracetam]]<br />
* [[S-18986]]<br />
* [[Sunifiram]]<br />
* [[Unifiram]]<br />
<br />
* '''Antagonists:''' [[ACEA-1011]]<br />
* [[ATPO]]<br />
* [[Becampanel]]<br />
* [[Caroverine]]<br />
* [[CNQX]]<br />
* [[Dasolampanel]]<br />
* [[DNQX]]<br />
* [[Fanapanel|Fanapanel (MPQX)]]<br />
* [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]<br />
* [[GYKI-52466]]<br />
* [[Kynurenic acid]]<br />
* [[Kynurenine]]<!--As a prodrug of kynurenic acid--><br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[NBQX]]<br />
* [[PNQX]]<br />
* [[Selurampanel]]<br />
* [[Tezampanel]]<br />
* [[Theanine]]<br />
* [[Topiramate]]<br />
* [[YM90K]]<br />
* [[Zonampanel]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])<br />
* [[Cyclopropane]]<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Evans blue]]<br />
* [[GYKI-53,655]]<br />
* [[Halothane]]<br />
* [[Irampanel]]<br />
* [[Isoflurane]]<br />
* [[Perampanel]]<br />
* [[Pregnenolone sulfate]]<br />
* [[Talampanel]]<br />
<br />
| group2 = [[NMDA receptor|NMDA]]<br />
| list2 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[2-Amino-2-(3-hydroxy-5-methylisoxazol-4-yl)acetic acid|AMAA]]<br />
* [[Aspartate]]<br />
* [[Glutamate]]<br />
* [[Homocysteic acid|Homocysteic acid (<small>L</small>-HCA)]]<br />
* [[Homoquinolinic acid]]<br />
* [[Ibotenic acid]]<br />
* [[N-Methyl-D-aspartic acid|NMDA]]<br />
* [[Proline]]<br />
* [[Quinolinic acid]]<br />
* [[Tetrazolylglycine]]<br />
* [[Theanine]]; ''Glycine site agonists:'' [[β-Fluoro-D-alanine|β-Fluoro-<small>D</small>-alanine]]<br />
* [[ACBD (drug)|ACBD]]<br />
* [[1-Aminocyclopropanecarboxylic acid|ACC (ACPC)]]<br />
* [[ACPD]]<br />
* [[AK-51 (drug)|AK-51]]<br />
* [[B6B21]]<br />
* [[Carboxycyclopropylglycine|CCG]]<br />
* [[Alanine|<small>D</small>-Alanine]]<br />
* [[Cycloserine|<small>D</small>-Cycloserine]]<br />
* [[Serine|<small>D</small>-Serine]]<br />
* [[N-(3,3-Diphenylpropyl)glycinamide|DHPG]]<br />
* [[Glycine]]<br />
* [[HA-966]]<br />
* [[L-687,414]]<br />
* [[Alanine|<small>L</small>-Alanine]]<br />
* [[Serine|<small>L</small>-Serine]]<br />
* [[Milacemide]]<br />
* [[Neboglamine|Neboglamine (nebostinel)]]<br />
* [[NRX-1074]]<br />
* [[Rapastinel|Rapastinel (GLYX-13)]]<br />
* [[Sarcosine]]; ''Polyamine site agonists:'' [[Spermidine]]<br />
* [[Spermine]]; ''Other positive allosteric modulators:'' [[24S-Hydroxycholesterol]]<br />
* [[Dehydroepiandrosterone|DHEA]]<br />
* [[Dehydroepiandrosterone sulfate|DHEA sulfate]]<br />
* [[Pregnenolone sulfate]]<br />
<br />
* '''Antagonists:''' ''Competitive antagonists:'' [[AP5|AP5 (APV)]]<br />
* [[AP-7 (drug)|AP7]]<br />
* [[CGP-37849]]<br />
* [[CGP-39551]]<br />
* [[CGP-39653]]<br />
* [[CGP-40116]]<br />
* [[CGS-19755]]<br />
* [[3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid|CPP]]<br />
* [[LY-233,053]]<br />
* [[LY-235,959]]<br />
* [[LY-274,614]]<br />
* [[MDL-100,453]]<br />
* [[Midafotel|Midafotel (d-CPPene)]]<br />
* [[NPC-12,626]]<br />
* [[NPC-17,742]]<br />
* [[PBPD]]<br />
* [[PEAQX]]<br />
* [[Perzinfotel]]<br />
* [[cis-1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid|PPDA]]<br />
* [[SDZ-220581]]<br />
* [[Selfotel]]; ''Noncompetitive antagonists:'' [[ARR-15,896]]<br />
* [[Caroverine]]<br />
* [[Dexanabinol]]<br />
* [[FPL-12495]]<br />
* [[FR-115,427]]<br />
* [[Hodgkinsine]]<br />
* [[Magnesium]]<br />
* [[MDL-27,266]]<br />
* [[NPS-1506]]<br />
* [[Psychotridine]]<br />
* [[Zinc]]; ''Uncompetitive pore blockers:'' [[2-MDP]]<br />
* [[3-HO-PCP]]<br />
* [[3-MeO-PCE]]<br />
* [[3-MeO-PCMo]]<br />
* [[3-MeO-PCP]]<br />
* [[4-MeO-PCP]]<br />
* [[8a-Phenyldecahydroquinoline|8A-PDHQ]]<br />
* [[18-Methoxycoronaridine|18-MC]]<br />
* [[Alpha-Endopsychosin|α-Endopsychosin]]<br />
* [[Alaproclate]]<br />
* [[Amantadine]]<br />
* [[Aptiganel]]<br />
* [[Arketamine]]<br />
* [[ARL-12,495]]<br />
* [[ARL-15,896-AR]]<br />
* [[ARL-16,247]]<br />
* [[Budipine]]<br />
* [[Conaridine]]<br />
* [[Delucemine]]<br />
* [[Dexoxadrol]]<br />
* [[Dextrallorphan]]<br />
* [[Dieticyclidine]]<br />
* [[Diphenidine]]<br />
* [[Dizocilpine]]<br />
* [[Ephenidine]]<br />
* [[Esketamine]]<br />
* [[Etoxadrol]]<br />
* [[Eticyclidine]]<br />
* [[Fluorolintane]]<br />
* [[Gacyclidine]]<br />
* [[Ibogaine]]<br />
* [[Ibogamine]]<br />
* [[Indantadol]]<br />
* [[Ketamine]]<br />
* [[Ketobemidone]]<br />
* [[Lanicemine]]<br />
* [[Loperamide]]<br />
* [[Memantine]]<br />
* [[Methadone]] ([[Levomethadone]])<br />
* [[Methorphan]] ([[Dextromethorphan]]<br />
* [[Levomethorphan]])<br />
* [[Methoxetamine]]<br />
* [[Methoxphenidine]]<br />
* [[Milnacipran]]<br />
* [[Morphanol]] ([[Dextrorphan]]<br />
* [[Levorphanol]])<br />
* [[NEFA (drug)|NEFA]]<br />
* [[Neramexane]]<br />
* [[Nitromemantine]]<br />
* [[Nitrous oxide]]<br />
* [[Noribogaine]]<br />
* [[Norketamine]]<br />
* [[Orphenadrine]]<br />
* [[PCPr]]<br />
* [[Pethidine|Pethidine (meperidine)]]<br />
* [[Phencyclamine]]<br />
* [[Phencyclidine]]<br />
* [[Propoxyphene]]<br />
* [[Remacemide]]<br />
* [[Rhynchophylline]]<br />
* [[Rimantadine]]<br />
* [[Rolicyclidine]]<br />
* [[Sabeluzole]]<br />
* [[Tabernanthine]]<br />
* [[Tenocyclidine]]<br />
* [[Tiletamine]]<br />
* [[Tramadol]]<br />
* [[Xenon]]; ''Glycine site antagonists:'' [[4-Chlorokynurenine|4-Cl-KYN (AV-101)]]<br />
* [[5,7-Dichlorokynurenic acid|5,7-DCKA]]<br />
* [[7-Chlorokynurenate|7-CKA]]<br />
* [[1-Aminocyclopropane-1-carboxylic acid|ACC]]<br />
* [[ACEA-1011]]<br />
* [[ACEA-1328]]<br />
* [[AV-101]]<br />
* [[Carisoprodol]]<br />
* [[CGP-39653]]<br />
* [[CNQX]]<br />
* [[DNQX]]<br />
* [[Felbamate]]<br />
* [[Gavestinel]]<br />
* [[GV-196,771]]<br />
* [[Kynurenic acid]]<br />
* [[Kynurenine]]<!--As a prodrug of kynurenic acid--><br />
* [[L-689,560]]<br />
* [[L-701,324]]<br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[LU-73,068]]<br />
* [[MDL-105,519]]<br />
* [[Meprobamate]]<br />
* [[MRZ 2/576]]<br />
* [[PNQX]]<br />
* [[ZD-9379]]; ''NR2B subunit antagonists:'' [[Besonprodil]]<br />
* [[CERC-301|CERC-301 (MK-0657)]]<br />
* [[CO-101,244|CO-101,244 (PD-174,494)]]<br />
* [[Eliprodil]]<br />
* [[Haloperidol]]<br />
* [[Ifenprodil]]<br />
* [[Isoxsuprine]]<br />
* [[Nylidrin]]<br />
* [[Ro8-4304]]<br />
* [[Ro25-6981]]<br />
* [[Traxoprodil]]; ''Polyamine site antagonists:'' [[Arcaine]]<br />
* [[Co 101676]]<br />
* [[1,3-Diaminopropane|Diaminopropane]]<br />
* [[Diethylenetriamine]]<br />
* [[Huperzine A]]<br />
* [[Putrescine]]<br />
* [[Ro 25-6981]]; ''Unclassified/unsorted antagonists:'' [[Bumetanide]]<br />
* [[Chloroform]]<br />
* [[Cyclopropane]]<br />
* [[D-α-Aminoadipate|<small>D</small>-αAA]]<br />
* [[Diethyl ether]]<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Flufenamic acid]]<br />
* [[Flupirtine]]<br />
* [[Furosemide]]<br />
* [[Halothane]]<br />
* [[Isoflurane]]<br />
* [[Metaphit]]<!--Irreversible--><br />
* [[Methoxyflurane]]<br />
* [[Niflumic acid]]<br />
* [[Piretanide]]<br />
* [[Toluene]]<br />
* [[Transcrocetin]] ([[saffron]])<br />
* [[1,1,1-Trichloroethane|Trichloroethane]]<br />
* [[2,2,2-Trichloroethanol|Trichloroethanol]]<br />
* [[Trichloroethylene]]<br />
* [[Xylene]]<br />
<br />
| group3 = [[Kainate receptor|Kainate]]<br />
| list3 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Bromowillardiine]]<br />
* [[5-Iodowillardiine]]<br />
* [[Acromelic acid|Acromelic acid (acromelate)]]<br />
* [[AMPA]]<br />
* [[ATPA]]<br />
* [[Domoic acid]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Kainic acid]]<br />
* [[LY-339,434]]<br />
* [[Proline]]<br />
* [[Quisqualic acid]]<br />
* [[SYM-2081]]; ''Positive allosteric modulators:'' [[Cyclothiazide]]<br />
* [[Diazoxide]]<br />
* [[Enflurane]]<br />
* [[Halothane]]<br />
* [[Isoflurane]]<br />
<br />
* '''Antagonists:''' [[ACEA-1011]]<br />
* [[CNQX]]<br />
* [[Dasolampanel]]<br />
* [[DNQX]]<br />
* [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]<br />
* [[Kynurenic acid]]<br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[LY-382,884]]<br />
* [[NBQX]]<br />
* [[NS102]]<br />
* [[Selurampanel]]<br />
* [[Tezampanel]]<br />
* [[Theanine]]<br />
* [[Topiramate]]<br />
* [[UBP-302]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Evans blue]]<br />
* [[NS-3763]]<br />
* [[Pregnenolone sulfate]]<br />
<br />
| group4 = [[Metabotropic glutamate receptor 1|mGlu<sub>1</sub>]]<br />
| list4 =<br />
* '''Agonists:''' [[ACPD]]<br />
* [[Dihydroxyphenylglycine|DHPG]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Quisqualic acid]]<br />
* [[Ro01-6128]]<br />
* [[Ro67-4853]]<br />
* [[Ro67-7476]]<br />
* [[VU-71]]<br />
<br />
* '''Antagonists:''' [[BAY 36-7620]]<br />
* [[CPCCOEt]]<br />
* [[Cyclothiazide]]<br />
* [[LY-367,385]]<br />
* [[LY-456,236]]<br />
* [[MCPG]]<br />
* [[NPS-2390]]<br />
<br />
| group5 = [[Metabotropic glutamate receptor 2|mGlu<sub>2</sub>]]<br />
| list5 =<br />
* '''Agonists:''' [[Biphenylindanone A|BINA]]<br />
* [[CBiPES]]<br />
* [[DCG-IV]]<br />
* [[Eglumegad]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[LY-379,268]]<br />
* [[LY-404,039|LY-404,039 (pomaglumetad)]]<br />
* [[LY-487,379]]<br />
* [[LY-566,332]]<br />
* [[MGS-0028]]<br />
* [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]<br />
* [[Talaglumetad]]; ''Positive allosteric modulators:'' [[JNJ-40411813|JNJ-40411813 (ADX-71149)]]<br />
<br />
* '''Antagonists:''' [[APICA (drug)|APICA]]<br />
* [[CECXG]]<br />
* [[EGLU]]<br />
* [[HYDIA]]<br />
* [[LY-307,452]]<br />
* [[LY-341,495]]<br />
* [[MCPG]]<br />
* [[MGS-0039]]<br />
* [[PCCG-4]]; ''Negative allosteric modulators:'' [[Decoglurant]]<br />
* [[RO4491533]]<br />
<br />
| group6 = [[Metabotropic glutamate receptor 3|mGlu<sub>3</sub>]]<br />
| list6 =<br />
* '''Agonists:''' [[CBiPES]]<br />
* [[DCG-IV]]<br />
* [[Eglumegad]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[LY-379,268]]<br />
* [[LY-404,039|LY-404,039 (pomaglumetad)]]<br />
* [[LY-487,379]]<br />
* [[MGS-0028]]<br />
* [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]<br />
* [[Talaglumetad]]<br />
<br />
* '''Antagonists:''' [[APICA (drug)|APICA]]<br />
* [[CECXG]]<br />
* [[EGLU]]<br />
* [[HYDIA]]<br />
* [[LY-307,452]]<br />
* [[LY-341,495]]<br />
* [[MCPG]]<br />
* [[MGS-0039]]; ''Negative allosteric modulators:'' [[Decoglurant]]<br />
* [[RO4491533]]<br />
<br />
| group7 = [[Metabotropic glutamate receptor 4|mGlu<sub>4</sub>]]<br />
| list7 =<br />
* '''Agonists:''' [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
* [[PHCCC]]<br />
* [[VU-001,171]]<br />
* [[VU-0155,041]]; ''Positive allosteric modulators:'' [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group8 = [[Metabotropic glutamate receptor 5|mGlu<sub>5</sub>]]<br />
| list8 =<br />
* '''Agonists:''' [[ACPD]]<br />
* [[ADX-47273]]<br />
* [[CDPPB]]<br />
* [[Chlorohydroxyphenylglycine|CHPG]]<br />
* [[1-(3-fluorophenyl)-N-((3-fluorophenyl)methylideneamino)methanimine|DFB]]<br />
* [[Dihydroxyphenylglycine|DHPG]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Quisqualic acid]]<br />
* [[VU-1545]]<br />
<br />
* '''Antagonists:''' [[CTEP]]<br />
* [[DMeOB]]<br />
* [[LY-344,545]]<br />
* [[Mavoglurant]]<br />
* [[MCPG]]<br />
* [[NPS-2390]]<br />
* [[Remeglurant]]<br />
* [[SIB-1757]]<br />
* [[SIB-1893]]; ''Negative allosteric modulators:'' [[Basimglurant]]<br />
* [[Dipraglurant]]<br />
* [[Fenobam]]<br />
* [[GRN-529]]<br />
* [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]<br />
* [[MTEP]]<br />
* [[Raseglurant]]<br />
<br />
| group9 = [[Metabotropic glutamate receptor 6|mGlu<sub>6</sub>]]<br />
| list9 =<br />
* '''Agonists:''' [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group10 = [[Metabotropic glutamate receptor 7|mGlu<sub>7</sub>]]<br />
| list10 =<br />
* '''Agonists:''' [[AMN082]]<br />
* [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[MMPIP]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group11 = [[Metabotropic glutamate receptor 8|mGlu<sub>8</sub>]]<br />
| list11 =<br />
* '''Agonists:''' [[DCPG]]<br />
* [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
}}<br />
<br />
| group2 = [[Neurotransmitter transporter|Transporter]]<br />{{smaller|([[Excitatory amino acid reuptake inhibitor|blockers]])}}<br />
| list2 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Glutamate transporter|EAATs]]<br />
| list1 =<br />
* [[Amphetamine]]<br />
* [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive--><br />
* [[cis-1-Aminocyclobutane-1,3-dicarboxylic acid|''cis''-ACBD]]<br />
* [[Dihydrokainic acid|DHKA]]<br />
* [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive--><br />
* [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-4-carboxylic acid|HIP-A]]<br />
* [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-6-carboxylic acid|HIP-B]]<br />
* [[Kainic acid]]<br />
* [[3-Hydroxyaspartic acid|<small>L</small>-(-)-''threo''-3-Hydroxyaspartic acid]]<br />
* [[L-α-Aminoadipate|<small>L</small>-αAA]]<br />
* [[(2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine|<small>L</small>-CCG-III ((2S,3S,4R)-CCG)]]<br />
* [[L-Serine-O-sulphate|<small>L</small>-Serine-O-sulphate (SOS)]]<br />
* [[L-trans-Pyrrolidine-2,4-dicarboxylic acid|<small>L</small>-''trans''-2,4-PDC]]<br />
* [[L-anti-endo-3,4-Methanopyrrolidinedicarboxylic acid|MPDC]]<br />
* [[SYM-2081]]<br />
* [[threo-β-Benzyloxyaspartic acid|TBOA]]<br />
* [[TFB-TBOA]]<br />
* [[Theanine]]<br />
* [[threo-3-Methylglutamic acid|''threo''-3-Methylglutamic acid]]<br />
* [[UCPH-101]]<br />
* [[WAY-213,613]]<br />
<br />
| group2 = [[Vesicular glutamate transporters|vGluTs]]<br />
| list2 =<br />
* [[4-Methylene-L-glutamate|4-Methylene-<small>L</small>-glutamate]]<br />
* [[6-(4'-Phenylstyryl)-quinoline-2,4-dicarboxylic acid|6-(4'-Phenylstyryl)-QDC]]<br />
* [[6-Biphenyl-4-yl-quinoline-2,4-dicarboxylic acid|6-Biphenyl-4-yl-QDC]]<br />
* [[7-Chlorokynurenic acid|7-CKA]]<br />
* [[Acid red 114]]<br />
* [[Amido black 10B|Amido black 10B (naphthol blue black)]]<br />
* [[Bafilomycin A1]]<br />
* [[Benzopurpurin 4B]]<br />
* [[Bumetamide]]<br />
* [[Chicago sky blue 6B]]<br />
* [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive--><br />
* [[DIDS]]<br />
* [[Direct blue 71]]<br />
* [[Erythro-4-methyl-L-glutamic acid|Erythro-4-methyl-<small>L</small>-glutamic acid]]<br />
* [[Evans blue]]<br />
* [[Furosemide]]<br />
* [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive--><br />
* [[Kynurenic acid]]<br />
* [[Nigericin]]<br />
* [[5-Nitro-2-(3-phenylpropylamino)benzoic acid|NPPB (N144)]]<br />
* [[Ponceau SS]]<br />
* [[Reactive blue 2]]<br />
* [[Rose bengal]]<br />
* [[4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid|SITS]]<br />
* [[Trans-1-aminocyclopentane-1,3-dicarboxylic acid|''trans''-ACDP]]<br />
* [[Trypan blue]]<br />
* [[Valinomycin]]<br />
* [[Xanthurenic acid]]<br />
<br />
}}<br />
<br />
| group3 = [[Enzyme]]<br />{{smaller|([[Enzyme inhibitor|inhibitors]])}}<br />
| list3 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Glutaminase|GAH]]<br />
| list1 =<br />
* [[BPTES]]<br />
* [[CB-839]]<br />
* [[6-Diazo-5-oxo-L-norleucine|DON]]<br />
<br />
| group2 = [[Aspartate aminotransferase|AST]]<br />
| list2 =<br />
* [[2-Amino-3-butenoic acid]]<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[L-2-Amino-4-methoxy-trans-3-butenoic acid|AMB]]<br />
* [[β-DL-Methylene-aspartate|β-{{smaller|DL}}-Methylene-aspartate]]<br />
* [[Hydrazinosuccinate]]<br />
<br />
| group3 = [[Alanine aminotransferase|ALT]]<br />
| list3 =<br />
* [[β-Chloro-L-alanine|β-Chloro-{{smaller|L}}-alanine]]<br />
* [[L-Cycloserine|{{smaller|L}}-Cycloserine]]<br />
* [[Propargylglycine]]<br />
<br />
| group4 = [[Glutamate dehydrogenase|GDH]]<br />
| list4 =<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[Bithionol]]<br />
* [[Chloroquine]]<br />
* [[Epigallocatechin-3-gallate|EGCG]]<br />
* [[Guanosine-5'-triphosphate|GTP]]<br />
* [[GW5074]]<br />
* [[Hexachlorophene]]<br />
* [[Hydroxylamine]]<br />
* [[Palmitoyl-coenzyme A|Palmitoyl-CoA]]<br />
* [[Pyridoxal phosphate]]<br />
<br />
| group5 = [[Glutamine synthetase|GS]]<br />
| list5 =<br />
* [[2-Aminoadipic acid]]<br />
* [[JFD01307SC]]<br />
* [[Methionine sulfoximine]]<br />
* [[Phosphinothricin|Phosphinothricin (glufosinate)]]<br />
<br />
| group6 = [[Glutamate decarboxylase|GAD]]<br />
| list6 =<br />
* [[3-Mercaptopropionic acid]]<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[L-Allylglycine|<small>L</small>-Allylglycine]]<br />
* [[Semicarbazide]]<br />
<br />
}}<br />
<br />
| group4 = Others<br />
| list4 =<br />
* '''Precursors:''' [[γ-Hydroxybutyric acid|GHB]]<!--PMID: 10381791--><br />
* [[Glutamine|<small>L</small>-Glutamine]]<br />
<br />
* '''Cofactors:''' [[α-Ketoglutaric acid]]<br />
* [[Iron]]<br />
* [[Sulfur]]<br />
* [[Vitamin B2|Vitamin B<sub>2</sub>]]<br />
* [[Vitamin B3|Vitamin B<sub>3</sub>]]<br />
<br />
* '''Others:''' [[Acamprosate]]<br />
* [[Cysteine]]<br />
* [[Cytidine]]<br />
* [[Cytisine]]<br />
* [[Glutathione]]<br />
* [[Glutathione disulfide]]<br />
* [[Minocycline]]<br />
* [[N-Acetylcysteine]]<br />
* [[Riluzole]]<br />
* [[S-Nitrosoglutathione]]<br />
* [[Tianeptine]]<br />
<br />
| below = '''''See also:''' [[Template:GABAergics|GABAergics]] • [[Template:GHBergics|GHBergics]] • [[Template:Glycinergics|Glycinergics]]''<br />
<br />
}}<noinclude><br />
{{collapsible option}}<br />
[[Category:Drug templates by receptor, channel, or pump]]<br />
</noinclude></div>
74.87.207.3
https://blackwiki.org/index.php?title=Template:Glutamate_receptor_modulators&diff=5492804
Template:Glutamate receptor modulators
2016-03-26T02:24:49Z
<p>74.87.207.3: </p>
<hr />
<div>{{Navbox<br />
| name = Glutamatergics<br />
| title = [[Glutamate]]rgics<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
| listclass = hlist<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Receptor (biochemistry)|Receptor]]<br />{{smaller|([[Ligand (biochemistry)|ligands]])}}<br />
| list1 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[AMPA receptor|AMPA]]<br />
| list1 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Fluorowillardiine]]<br />
* [[Acromelic acid|Acromelic acid (acromelate)]]<br />
* [[AMPA]]<br />
* [[β-N-Oxalylamino-L-Alanine|BOAA]]<br />
* [[Domoic acid]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Proline]]<br />
* [[Quisqualic acid]]<br />
* [[Willardiine]]; ''Positive allosteric modulators:'' [[Aniracetam]]<br />
* [[Cyclothiazide]]<br />
* [[CX-516]]<br />
* [[CX-546]]<br />
* [[CX-614]]<br />
* [[Farampator|Farampator (CX-691, Org 24448)]]<br />
* [[CX-717]]<br />
* [[CX-1739]]<br />
* [[CX-1942]]<br />
* [[Diazoxide]]<br />
* [[Hydrochlorothiazide|Hydrochlorothiazide (HCTZ)]]<br />
* [[IDRA-21]]<br />
* [[LY-392,098]]<br />
* [[LY-404,187]]<br />
* [[LY-451,646]]<br />
* [[LY-503,430]]<br />
* [[Mibampator|Mibampator (LY-451,395)]]<br />
* [[Org 26576]]<br />
* [[Oxiracetam]]<br />
* [[PEPA (drug)|PEPA]]<br />
* [[PF-04958242]]<br />
* [[Piracetam]]<br />
* [[Pramiracetam]]<br />
* [[S-18986]]<br />
* [[Sunifiram]]<br />
* [[Unifiram]]<br />
<br />
* '''Antagonists:''' [[ACEA-1011]]<br />
* [[ATPO]]<br />
* [[Becampanel]]<br />
* [[Caroverine]]<br />
* [[CNQX]]<br />
* [[Dasolampanel]]<br />
* [[DNQX]]<br />
* [[Fanapanel|Fanapanel (MPQX)]]<br />
* [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]<br />
* [[GYKI-52466]]<br />
* [[Kynurenic acid]]<br />
* [[Kynurenine]]<!--As a prodrug of kynurenic acid--><br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[NBQX]]<br />
* [[PNQX]]<br />
* [[Selurampanel]]<br />
* [[Tezampanel]]<br />
* [[Theanine]]<br />
* [[Topiramate]]<br />
* [[YM90K]]<br />
* [[Zonampanel]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])<br />
* [[Cyclopropane]]<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Evans blue]]<br />
* [[GYKI-53,655]]<br />
* [[Halothane]]<br />
* [[Irampanel]]<br />
* [[Isoflurane]]<br />
* [[Perampanel]]<br />
* [[Pregnenolone sulfate]]<br />
* [[Talampanel]]<br />
<br />
| group2 = [[NMDA receptor|NMDA]]<br />
| list2 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[2-Amino-2-(3-hydroxy-5-methylisoxazol-4-yl)acetic acid|AMAA]]<br />
* [[Aspartate]]<br />
* [[Glutamate]]<br />
* [[Homocysteic acid|Homocysteic acid (<small>L</small>-HCA)]]<br />
* [[Homoquinolinic acid]]<br />
* [[Ibotenic acid]]<br />
* [[N-Methyl-D-aspartic acid|NMDA]]<br />
* [[Proline]]<br />
* [[Quinolinic acid]]<br />
* [[Tetrazolylglycine]]<br />
* [[Theanine]]; ''Glycine site agonists:'' [[β-Fluoro-D-alanine|β-Fluoro-<small>D</small>-alanine]]<br />
* [[ACBD (drug)|ACBD]]<br />
* [[1-Aminocyclopropanecarboxylic acid|ACC (ACPC)]]<br />
* [[ACPD]]<br />
* [[AK-51 (drug)|AK-51]]<br />
* [[B6B21]]<br />
* [[Carboxycyclopropylglycine|CCG]]<br />
* [[Alanine|<small>D</small>-Alanine]]<br />
* [[Cycloserine|<small>D</small>-Cycloserine]]<br />
* [[Serine|<small>D</small>-Serine]]<br />
* [[N-(3,3-Diphenylpropyl)glycinamide|DHPG]]<br />
* [[Glycine]]<br />
* [[HA-966]]<br />
* [[L-687,414]]<br />
* [[Alanine|<small>L</small>-Alanine]]<br />
* [[Serine|<small>L</small>-Serine]]<br />
* [[Milacemide]]<br />
* [[Neboglamine]]<br />
* [[NRX-1074]]<br />
* [[Rapastinel|Rapastinel (GLYX-13)]]<br />
* [[Sarcosine]]; ''Polyamine site agonists:'' [[Spermidine]]<br />
* [[Spermine]]; ''Other positive allosteric modulators:'' [[24S-Hydroxycholesterol]]<br />
* [[Dehydroepiandrosterone|DHEA]]<br />
* [[Dehydroepiandrosterone sulfate|DHEA sulfate]]<br />
* [[Pregnenolone sulfate]]<br />
<br />
* '''Antagonists:''' ''Competitive antagonists:'' [[AP5|AP5 (APV)]]<br />
* [[AP-7 (drug)|AP7]]<br />
* [[CGP-37849]]<br />
* [[CGP-39551]]<br />
* [[CGP-39653]]<br />
* [[CGP-40116]]<br />
* [[CGS-19755]]<br />
* [[3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid|CPP]]<br />
* [[LY-233,053]]<br />
* [[LY-235,959]]<br />
* [[LY-274,614]]<br />
* [[MDL-100,453]]<br />
* [[Midafotel|Midafotel (d-CPPene)]]<br />
* [[NPC-12,626]]<br />
* [[NPC-17,742]]<br />
* [[PBPD]]<br />
* [[PEAQX]]<br />
* [[Perzinfotel]]<br />
* [[cis-1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid|PPDA]]<br />
* [[SDZ-220581]]<br />
* [[Selfotel]]; ''Noncompetitive antagonists:'' [[ARR-15,896]]<br />
* [[Caroverine]]<br />
* [[Dexanabinol]]<br />
* [[FPL-12495]]<br />
* [[FR-115,427]]<br />
* [[Hodgkinsine]]<br />
* [[Magnesium]]<br />
* [[MDL-27,266]]<br />
* [[NPS-1506]]<br />
* [[Psychotridine]]<br />
* [[Zinc]]; ''Uncompetitive pore blockers:'' [[2-MDP]]<br />
* [[3-HO-PCP]]<br />
* [[3-MeO-PCE]]<br />
* [[3-MeO-PCMo]]<br />
* [[3-MeO-PCP]]<br />
* [[4-MeO-PCP]]<br />
* [[8a-Phenyldecahydroquinoline|8A-PDHQ]]<br />
* [[18-Methoxycoronaridine|18-MC]]<br />
* [[Alpha-Endopsychosin|α-Endopsychosin]]<br />
* [[Alaproclate]]<br />
* [[Amantadine]]<br />
* [[Aptiganel]]<br />
* [[Arketamine]]<br />
* [[ARL-12,495]]<br />
* [[ARL-15,896-AR]]<br />
* [[ARL-16,247]]<br />
* [[Budipine]]<br />
* [[Conaridine]]<br />
* [[Delucemine]]<br />
* [[Dexoxadrol]]<br />
* [[Dextrallorphan]]<br />
* [[Dieticyclidine]]<br />
* [[Diphenidine]]<br />
* [[Dizocilpine]]<br />
* [[Ephenidine]]<br />
* [[Esketamine]]<br />
* [[Etoxadrol]]<br />
* [[Eticyclidine]]<br />
* [[Fluorolintane]]<br />
* [[Gacyclidine]]<br />
* [[Ibogaine]]<br />
* [[Ibogamine]]<br />
* [[Indantadol]]<br />
* [[Ketamine]]<br />
* [[Ketobemidone]]<br />
* [[Lanicemine]]<br />
* [[Loperamide]]<br />
* [[Memantine]]<br />
* [[Methadone]] ([[Levomethadone]])<br />
* [[Methorphan]] ([[Dextromethorphan]]<br />
* [[Levomethorphan]])<br />
* [[Methoxetamine]]<br />
* [[Methoxphenidine]]<br />
* [[Milnacipran]]<br />
* [[Morphanol]] ([[Dextrorphan]]<br />
* [[Levorphanol]])<br />
* [[NEFA (drug)|NEFA]]<br />
* [[Neramexane]]<br />
* [[Nitromemantine]]<br />
* [[Nitrous oxide]]<br />
* [[Noribogaine]]<br />
* [[Norketamine]]<br />
* [[Orphenadrine]]<br />
* [[PCPr]]<br />
* [[Pethidine|Pethidine (meperidine)]]<br />
* [[Phencyclamine]]<br />
* [[Phencyclidine]]<br />
* [[Propoxyphene]]<br />
* [[Remacemide]]<br />
* [[Rhynchophylline]]<br />
* [[Rimantadine]]<br />
* [[Rolicyclidine]]<br />
* [[Sabeluzole]]<br />
* [[Tabernanthine]]<br />
* [[Tenocyclidine]]<br />
* [[Tiletamine]]<br />
* [[Tramadol]]<br />
* [[Xenon]]; ''Glycine site antagonists:'' [[4-Chlorokynurenine|4-Cl-KYN (AV-101)]]<br />
* [[5,7-Dichlorokynurenic acid|5,7-DCKA]]<br />
* [[7-Chlorokynurenate|7-CKA]]<br />
* [[1-Aminocyclopropane-1-carboxylic acid|ACC]]<br />
* [[ACEA-1011]]<br />
* [[ACEA-1328]]<br />
* [[AV-101]]<br />
* [[Carisoprodol]]<br />
* [[CGP-39653]]<br />
* [[CNQX]]<br />
* [[DNQX]]<br />
* [[Felbamate]]<br />
* [[Gavestinel]]<br />
* [[GV-196,771]]<br />
* [[Kynurenic acid]]<br />
* [[Kynurenine]]<!--As a prodrug of kynurenic acid--><br />
* [[L-689,560]]<br />
* [[L-701,324]]<br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[LU-73,068]]<br />
* [[MDL-105,519]]<br />
* [[Meprobamate]]<br />
* [[MRZ 2/576]]<br />
* [[PNQX]]<br />
* [[ZD-9379]]; ''NR2B subunit antagonists:'' [[Besonprodil]]<br />
* [[CERC-301|CERC-301 (MK-0657)]]<br />
* [[CO-101,244|CO-101,244 (PD-174,494)]]<br />
* [[Eliprodil]]<br />
* [[Haloperidol]]<br />
* [[Ifenprodil]]<br />
* [[Isoxsuprine]]<br />
* [[Nylidrin]]<br />
* [[Ro8-4304]]<br />
* [[Ro25-6981]]<br />
* [[Traxoprodil]]; ''Polyamine site antagonists:'' [[Arcaine]]<br />
* [[Co 101676]]<br />
* [[1,3-Diaminopropane|Diaminopropane]]<br />
* [[Diethylenetriamine]]<br />
* [[Huperzine A]]<br />
* [[Putrescine]]<br />
* [[Ro 25-6981]]; ''Unclassified/unsorted antagonists:'' [[Bumetanide]]<br />
* [[Chloroform]]<br />
* [[Cyclopropane]]<br />
* [[D-α-Aminoadipate|<small>D</small>-αAA]]<br />
* [[Diethyl ether]]<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Flufenamic acid]]<br />
* [[Flupirtine]]<br />
* [[Furosemide]]<br />
* [[Halothane]]<br />
* [[Isoflurane]]<br />
* [[Metaphit]]<!--Irreversible--><br />
* [[Methoxyflurane]]<br />
* [[Niflumic acid]]<br />
* [[Piretanide]]<br />
* [[Toluene]]<br />
* [[Transcrocetin]] ([[saffron]])<br />
* [[1,1,1-Trichloroethane|Trichloroethane]]<br />
* [[2,2,2-Trichloroethanol|Trichloroethanol]]<br />
* [[Trichloroethylene]]<br />
* [[Xylene]]<br />
<br />
| group3 = [[Kainate receptor|Kainate]]<br />
| list3 =<br />
* '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Bromowillardiine]]<br />
* [[5-Iodowillardiine]]<br />
* [[Acromelic acid|Acromelic acid (acromelate)]]<br />
* [[AMPA]]<br />
* [[ATPA]]<br />
* [[Domoic acid]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Kainic acid]]<br />
* [[LY-339,434]]<br />
* [[Proline]]<br />
* [[Quisqualic acid]]<br />
* [[SYM-2081]]; ''Positive allosteric modulators:'' [[Cyclothiazide]]<br />
* [[Diazoxide]]<br />
* [[Enflurane]]<br />
* [[Halothane]]<br />
* [[Isoflurane]]<br />
<br />
* '''Antagonists:''' [[ACEA-1011]]<br />
* [[CNQX]]<br />
* [[Dasolampanel]]<br />
* [[DNQX]]<br />
* [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]<br />
* [[Kynurenic acid]]<br />
* [[Licostinel|Licostinel (ACEA-1021)]]<br />
* [[LY-382,884]]<br />
* [[NBQX]]<br />
* [[NS102]]<br />
* [[Selurampanel]]<br />
* [[Tezampanel]]<br />
* [[Theanine]]<br />
* [[Topiramate]]<br />
* [[UBP-302]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])<br />
* [[Enflurane]]<br />
* [[Ethanol]]<br />
* [[Evans blue]]<br />
* [[NS-3763]]<br />
* [[Pregnenolone sulfate]]<br />
<br />
| group4 = [[Metabotropic glutamate receptor 1|mGlu<sub>1</sub>]]<br />
| list4 =<br />
* '''Agonists:''' [[ACPD]]<br />
* [[Dihydroxyphenylglycine|DHPG]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Quisqualic acid]]<br />
* [[Ro01-6128]]<br />
* [[Ro67-4853]]<br />
* [[Ro67-7476]]<br />
* [[VU-71]]<br />
<br />
* '''Antagonists:''' [[BAY 36-7620]]<br />
* [[CPCCOEt]]<br />
* [[Cyclothiazide]]<br />
* [[LY-367,385]]<br />
* [[LY-456,236]]<br />
* [[MCPG]]<br />
* [[NPS-2390]]<br />
<br />
| group5 = [[Metabotropic glutamate receptor 2|mGlu<sub>2</sub>]]<br />
| list5 =<br />
* '''Agonists:''' [[Biphenylindanone A|BINA]]<br />
* [[CBiPES]]<br />
* [[DCG-IV]]<br />
* [[Eglumegad]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[LY-379,268]]<br />
* [[LY-404,039|LY-404,039 (pomaglumetad)]]<br />
* [[LY-487,379]]<br />
* [[LY-566,332]]<br />
* [[MGS-0028]]<br />
* [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]<br />
* [[Talaglumetad]]; ''Positive allosteric modulators:'' [[JNJ-40411813|JNJ-40411813 (ADX-71149)]]<br />
<br />
* '''Antagonists:''' [[APICA (drug)|APICA]]<br />
* [[CECXG]]<br />
* [[EGLU]]<br />
* [[HYDIA]]<br />
* [[LY-307,452]]<br />
* [[LY-341,495]]<br />
* [[MCPG]]<br />
* [[MGS-0039]]<br />
* [[PCCG-4]]; ''Negative allosteric modulators:'' [[Decoglurant]]<br />
* [[RO4491533]]<br />
<br />
| group6 = [[Metabotropic glutamate receptor 3|mGlu<sub>3</sub>]]<br />
| list6 =<br />
* '''Agonists:''' [[CBiPES]]<br />
* [[DCG-IV]]<br />
* [[Eglumegad]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[LY-379,268]]<br />
* [[LY-404,039|LY-404,039 (pomaglumetad)]]<br />
* [[LY-487,379]]<br />
* [[MGS-0028]]<br />
* [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]<br />
* [[Talaglumetad]]<br />
<br />
* '''Antagonists:''' [[APICA (drug)|APICA]]<br />
* [[CECXG]]<br />
* [[EGLU]]<br />
* [[HYDIA]]<br />
* [[LY-307,452]]<br />
* [[LY-341,495]]<br />
* [[MCPG]]<br />
* [[MGS-0039]]; ''Negative allosteric modulators:'' [[Decoglurant]]<br />
* [[RO4491533]]<br />
<br />
| group7 = [[Metabotropic glutamate receptor 4|mGlu<sub>4</sub>]]<br />
| list7 =<br />
* '''Agonists:''' [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
* [[PHCCC]]<br />
* [[VU-001,171]]<br />
* [[VU-0155,041]]; ''Positive allosteric modulators:'' [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group8 = [[Metabotropic glutamate receptor 5|mGlu<sub>5</sub>]]<br />
| list8 =<br />
* '''Agonists:''' [[ACPD]]<br />
* [[ADX-47273]]<br />
* [[CDPPB]]<br />
* [[Chlorohydroxyphenylglycine|CHPG]]<br />
* [[1-(3-fluorophenyl)-N-((3-fluorophenyl)methylideneamino)methanimine|DFB]]<br />
* [[Dihydroxyphenylglycine|DHPG]]<br />
* [[Glutamate]]<br />
* [[Ibotenic acid]]<br />
* [[Quisqualic acid]]<br />
* [[VU-1545]]<br />
<br />
* '''Antagonists:''' [[CTEP]]<br />
* [[DMeOB]]<br />
* [[LY-344,545]]<br />
* [[Mavoglurant]]<br />
* [[MCPG]]<br />
* [[NPS-2390]]<br />
* [[Remeglurant]]<br />
* [[SIB-1757]]<br />
* [[SIB-1893]]; ''Negative allosteric modulators:'' [[Basimglurant]]<br />
* [[Dipraglurant]]<br />
* [[Fenobam]]<br />
* [[GRN-529]]<br />
* [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]<br />
* [[MTEP]]<br />
* [[Raseglurant]]<br />
<br />
| group9 = [[Metabotropic glutamate receptor 6|mGlu<sub>6</sub>]]<br />
| list9 =<br />
* '''Agonists:''' [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group10 = [[Metabotropic glutamate receptor 7|mGlu<sub>7</sub>]]<br />
| list10 =<br />
* '''Agonists:''' [[AMN082]]<br />
* [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[MMPIP]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
| group11 = [[Metabotropic glutamate receptor 8|mGlu<sub>8</sub>]]<br />
| list11 =<br />
* '''Agonists:''' [[DCPG]]<br />
* [[Glutamate]]<br />
* [[L-AP4|<small>L</small>-AP4]]<br />
<br />
* '''Antagonists:''' [[CPPG]]<br />
* [[MAP4 (drug)|MAP4]]<br />
* [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]<br />
* [[MSOP (drug)|MSOP]]<br />
* [[MTPG]]<br />
* [[UBP-1112]]<br />
<br />
}}<br />
<br />
| group2 = [[Neurotransmitter transporter|Transporter]]<br />{{smaller|([[Excitatory amino acid reuptake inhibitor|blockers]])}}<br />
| list2 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Glutamate transporter|EAATs]]<br />
| list1 =<br />
* [[Amphetamine]]<br />
* [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive--><br />
* [[cis-1-Aminocyclobutane-1,3-dicarboxylic acid|''cis''-ACBD]]<br />
* [[Dihydrokainic acid|DHKA]]<br />
* [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive--><br />
* [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-4-carboxylic acid|HIP-A]]<br />
* [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-6-carboxylic acid|HIP-B]]<br />
* [[Kainic acid]]<br />
* [[3-Hydroxyaspartic acid|<small>L</small>-(-)-''threo''-3-Hydroxyaspartic acid]]<br />
* [[L-α-Aminoadipate|<small>L</small>-αAA]]<br />
* [[(2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine|<small>L</small>-CCG-III ((2S,3S,4R)-CCG)]]<br />
* [[L-Serine-O-sulphate|<small>L</small>-Serine-O-sulphate (SOS)]]<br />
* [[L-trans-Pyrrolidine-2,4-dicarboxylic acid|<small>L</small>-''trans''-2,4-PDC]]<br />
* [[L-anti-endo-3,4-Methanopyrrolidinedicarboxylic acid|MPDC]]<br />
* [[SYM-2081]]<br />
* [[threo-β-Benzyloxyaspartic acid|TBOA]]<br />
* [[TFB-TBOA]]<br />
* [[Theanine]]<br />
* [[threo-3-Methylglutamic acid|''threo''-3-Methylglutamic acid]]<br />
* [[UCPH-101]]<br />
* [[WAY-213,613]]<br />
<br />
| group2 = [[Vesicular glutamate transporters|vGluTs]]<br />
| list2 =<br />
* [[4-Methylene-L-glutamate|4-Methylene-<small>L</small>-glutamate]]<br />
* [[6-(4'-Phenylstyryl)-quinoline-2,4-dicarboxylic acid|6-(4'-Phenylstyryl)-QDC]]<br />
* [[6-Biphenyl-4-yl-quinoline-2,4-dicarboxylic acid|6-Biphenyl-4-yl-QDC]]<br />
* [[7-Chlorokynurenic acid|7-CKA]]<br />
* [[Acid red 114]]<br />
* [[Amido black 10B|Amido black 10B (naphthol blue black)]]<br />
* [[Bafilomycin A1]]<br />
* [[Benzopurpurin 4B]]<br />
* [[Bumetamide]]<br />
* [[Chicago sky blue 6B]]<br />
* [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive--><br />
* [[DIDS]]<br />
* [[Direct blue 71]]<br />
* [[Erythro-4-methyl-L-glutamic acid|Erythro-4-methyl-<small>L</small>-glutamic acid]]<br />
* [[Evans blue]]<br />
* [[Furosemide]]<br />
* [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive--><br />
* [[Kynurenic acid]]<br />
* [[Nigericin]]<br />
* [[5-Nitro-2-(3-phenylpropylamino)benzoic acid|NPPB (N144)]]<br />
* [[Ponceau SS]]<br />
* [[Reactive blue 2]]<br />
* [[Rose bengal]]<br />
* [[4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid|SITS]]<br />
* [[Trans-1-aminocyclopentane-1,3-dicarboxylic acid|''trans''-ACDP]]<br />
* [[Trypan blue]]<br />
* [[Valinomycin]]<br />
* [[Xanthurenic acid]]<br />
<br />
}}<br />
<br />
| group3 = [[Enzyme]]<br />{{smaller|([[Enzyme inhibitor|inhibitors]])}}<br />
| list3 = {{Navbox|child<br />
| groupstyle = text-align:center;<br />
<br />
| group1 = [[Glutaminase|GAH]]<br />
| list1 =<br />
* [[BPTES]]<br />
* [[CB-839]]<br />
* [[6-Diazo-5-oxo-L-norleucine|DON]]<br />
<br />
| group2 = [[Aspartate aminotransferase|AST]]<br />
| list2 =<br />
* [[2-Amino-3-butenoic acid]]<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[L-2-Amino-4-methoxy-trans-3-butenoic acid|AMB]]<br />
* [[β-DL-Methylene-aspartate|β-{{smaller|DL}}-Methylene-aspartate]]<br />
* [[Hydrazinosuccinate]]<br />
<br />
| group3 = [[Alanine aminotransferase|ALT]]<br />
| list3 =<br />
* [[β-Chloro-L-alanine|β-Chloro-{{smaller|L}}-alanine]]<br />
* [[L-Cycloserine|{{smaller|L}}-Cycloserine]]<br />
* [[Propargylglycine]]<br />
<br />
| group4 = [[Glutamate dehydrogenase|GDH]]<br />
| list4 =<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[Bithionol]]<br />
* [[Chloroquine]]<br />
* [[Epigallocatechin-3-gallate|EGCG]]<br />
* [[Guanosine-5'-triphosphate|GTP]]<br />
* [[GW5074]]<br />
* [[Hexachlorophene]]<br />
* [[Hydroxylamine]]<br />
* [[Palmitoyl-coenzyme A|Palmitoyl-CoA]]<br />
* [[Pyridoxal phosphate]]<br />
<br />
| group5 = [[Glutamine synthetase|GS]]<br />
| list5 =<br />
* [[2-Aminoadipic acid]]<br />
* [[JFD01307SC]]<br />
* [[Methionine sulfoximine]]<br />
* [[Phosphinothricin|Phosphinothricin (glufosinate)]]<br />
<br />
| group6 = [[Glutamate decarboxylase|GAD]]<br />
| list6 =<br />
* [[3-Mercaptopropionic acid]]<br />
* [[Aminooxyacetic acid|AAOA]]<br />
* [[L-Allylglycine|<small>L</small>-Allylglycine]]<br />
* [[Semicarbazide]]<br />
<br />
}}<br />
<br />
| group4 = Others<br />
| list4 =<br />
* '''Precursors:''' [[γ-Hydroxybutyric acid|GHB]]<!--PMID: 10381791--><br />
* [[Glutamine|<small>L</small>-Glutamine]]<br />
<br />
* '''Cofactors:''' [[α-Ketoglutaric acid]]<br />
* [[Iron]]<br />
* [[Sulfur]]<br />
* [[Vitamin B2|Vitamin B<sub>2</sub>]]<br />
* [[Vitamin B3|Vitamin B<sub>3</sub>]]<br />
<br />
* '''Others:''' [[Acamprosate]]<br />
* [[Cysteine]]<br />
* [[Cytidine]]<br />
* [[Cytisine]]<br />
* [[Glutathione]]<br />
* [[Glutathione disulfide]]<br />
* [[Minocycline]]<br />
* [[N-Acetylcysteine]]<br />
* [[Riluzole]]<br />
* [[S-Nitrosoglutathione]]<br />
* [[Tianeptine]]<br />
<br />
| below = '''''See also:''' [[Template:GABAergics|GABAergics]] • [[Template:GHBergics|GHBergics]] • [[Template:Glycinergics|Glycinergics]]''<br />
<br />
}}<noinclude><br />
{{collapsible option}}<br />
[[Category:Drug templates by receptor, channel, or pump]]<br />
</noinclude></div>
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