Difference between revisions of "Template:Chemotherapeutic agents"

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{{Navbox
 
{{Navbox
| name = Intracellular chemotherapeutic agents
+
| name = Chemotherapeutic agents
|state = {{{state|collapsed}}}
+
| title = Intracellular [[Chemotherapy|chemotherapeutic agents]] / [[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]])
| title = Intracellular [[Chemotherapy (oncology)|chemotherapeutic agents]]/[[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]])
+
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| groupstyle = background-color: Plum
+
| listclass = hlist
  
  | group1 = [[Spindle poison|SP]]s/[[mitotic inhibitor|MI]]s<BR>([[M phase]])
+
| group1 = [[Spindle poison|SP]]s/[[Mitotic inhibitor|MI]]s<br />([[M phase]])
  | list1 = {{Navbox subgroup
+
| list1 = {{Navbox|child
| groupstyle = background-color: Plum
 
  
| group1 = Block [[microtubule]] assembly
+
  | group1 = Block [[microtubule]] assembly
| list1 = ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]], [[Vincristine]], [[Vinflunine]], [[Vindesine]], [[Vinorelbine]])
+
  | list1 =
 +
* ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup>
 +
* [[Vincristine]]<sup>#</sup>
 +
* [[Vindesine]]
 +
* [[Vinflunine]]<sup>§</sup>
 +
* [[Vinorelbine]]<sup>#</sup>)
  
| group2 = Block microtubule disassembly
+
  | group2 = Block microtubule disassembly
| list2 = ''[[Taxane]]s'' ([[Docetaxel]], [[Larotaxel]], [[Ortataxel]], [[Paclitaxel]], [[Tesetaxel]]){{·}} ''[[Epothilone]]s'' ([[Ixabepilone]])
+
  | list2 =
 +
* ''[[Taxane]]s'' ([[Cabazitaxel]]
 +
* [[Docetaxel]]<sup>#</sup>
 +
* [[Larotaxel]]
 +
* [[Ortataxel]]<sup>†</sup>
 +
* [[Paclitaxel]]<sup>#</sup>
 +
* [[Tesetaxel]])
 +
* ''[[Epothilone]]s'' ([[Ixabepilone]])
  
}}
+
}}
  
  | group2 = [[DNA replication]]<BR>inhibitor
+
| group2 = [[DNA replication]]<br />inhibitor
  | list2 = {{Navbox subgroup
+
| list2 = {{Navbox|child
  | groupstyle = background-color: Plum
 
  
| group1 = DNA precursors/<BR>[[antimetabolite]]s<BR>([[S phase]])
+
  | group1 = DNA precursors/<br />[[antimetabolite]]s<br />([[S phase]])
| list1 = {{Navbox subgroup
+
  | list1 = {{Navbox|child
  | groupstyle = background-color: Plum
 
  
 +
    | group1 = [[Antifolate|Folic acid]]
 +
    | list1 =
 +
* ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]]
 +
* [[Methotrexate]]<sup>#</sup>
 +
* [[Pemetrexed]]
 +
* [[Pralatrexate]])
 +
* ''[[Thymidylate synthase inhibitor]]'' ([[Pemetrexed]]
 +
* [[Raltitrexed]])
  
| group1 = [[Antifolate|Folic acid]]
+
    | group2 = [[Purine analogue|Purine]]
| list1  = ''[[dihydrofolate reductase inhibitor]]'' ([[Aminopterin]], [[Methotrexate]], [[Pemetrexed]], [[Pralatrexate]]){{·}} ''[[thymidylate synthase inhibitor]]'' ([[Raltitrexed]], [[Pemetrexed]])
+
    | list2 =
 +
* ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]])
  
| group2 = [[Purine analogue|Purine]]
+
* ''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]]
| list2  = ''[[adenosine deaminase inhibitor]]'' ([[Pentostatin]])
+
* [[Clofarabine]]
 +
* [[Fludarabine]])
 +
* [[Nelarabine]]
  
''[[halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]], [[Clofarabine]], [[Fludarabine]])<BR>
+
* ''[[Thiopurine]]'' ([[Mercaptopurine]]<sup>#</sup>
 +
* [[Tioguanine]]<sup>#</sup>)
  
''[[thiopurine]]'' ([[Tioguanine|Thioguanine]], [[Mercaptopurine]])
+
    | group3 = [[Pyrimidine analogue|Pyrimidine]]
 +
    | list3 =
 +
* ''[[Thymidylate synthase inhibitor]]'' ([[Capecitabine]]<sup>#</sup>
 +
* [[Carmofur]]
 +
* [[Doxifluridine]]
 +
* [[Floxuridine]]
 +
* [[Fluorouracil]]<sup>#</sup>
 +
* [[Tegafur]] ([[Tegafur/gimeracil/oteracil|+gimeracil/oteracil]]))
  
|group3  = [[Pyrimidine analogue|Pyrimidine]]
+
* ''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>)
|list3  = ''[[thymidylate synthase inhibitor]]'' ([[Fluorouracil]], [[Capecitabine]], [[Tegafur]], [[Carmofur]], [[Floxuridine]])
 
  
''[[DNA polymerase inhibitor]]'' ([[Cytarabine]])
+
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]]<sup>#</sup>)
  
''[[ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]])
+
* ''[[Hypomethylating agent]]'' ([[Azacitidine]]
 +
* [[Decitabine]])
  
''[[hypomethylating agent]]'' ([[Azacitidine]], [[Decitabine]])
+
    | group4 = [[Deoxyribonucleotide]]
 +
    | list4 =
 +
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]]<sup>#</sup>)
  
|group4  = [[Deoxyribonucleotide]]
+
  }}
|list4  = ''[[ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]])
 
  
}}
+
  | group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]])
 +
  | list2 = {{Navbox|child
  
| group2 = [[Topoisomerase inhibitor]]s<BR>([[S phase]])
+
    | group1 = [[Type I topoisomerase#Inhibition|I]]
| list2  = {{Navbox subgroup
+
    | list1 =
| groupstyle = background-color: Plum
+
* ''[[Camptotheca]]'' ([[Belotecan]]
 +
* [[Camptothecin]]
 +
* [[Cositecan]]<sup>†</sup>
 +
* [[Exatecan]]
 +
* [[Gimatecan]]
 +
* [[Irinotecan]]<sup>#</sup>
 +
* [[Lurtotecan]]<sup>‡</sup>
 +
* [[Rubitecan]]<sup>‡</sup>
 +
* [[Silatecan]]<sup>§</sup>
 +
* [[Topotecan]])
  
| group1 = [[Topoisomerase_I#Inhibition|I]]
+
    | group2 = [[Type II topoisomerase#Inhibition|II]]
| list1  = ''[[Camptotheca]]'' ([[Camptothecin]], [[Topotecan]], [[Irinotecan]], [[Rubitecan]], [[Belotecan]])
+
    | list2 =
 +
* ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup>
 +
* [[Teniposide]])
  
| group2 = [[Topoisomerase_II#Inhibition|II]]
+
    | group3 = [[Type II topoisomerase#Inhibition|II]]+[[Intercalation (biochemistry)|Intercalation]]
| list2  = ''[[American Mayapple|Podophyllum]]'' ([[Etoposide]], [[Teniposide]])
+
    | list3 =
 +
* ''[[Anthracycline]]s'' ([[Aclarubicin]]
 +
* [[Amrubicin]]<sup>†</sup>
 +
* [[Daunorubicin]]<sup>#</sup>
 +
* [[Doxorubicin]]<sup>#</sup>
 +
* [[Epirubicin]]
 +
* [[Idarubicin]]
 +
* [[Pirarubicin]]
 +
* [[Valrubicin]]
 +
* [[Zorubicin]])
 +
* ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]]
 +
* [[Losoxantrone]]
 +
* [[Pixantrone]])
  
| group3 = [[Topoisomerase_II#Inhibition|II]]+[[Intercalation (chemistry)|Intercalation]]
+
  }}
| list3  = ''[[Anthracycline]]s'' ([[Aclarubicin]], [[Daunorubicin]], [[Doxorubicin]], [[Epirubicin]], [[Idarubicin]], [[Amrubicin]], [[Pirarubicin]], [[Valrubicin]], [[Zorubicin]]){{·}} ''[[Anthracenedione]]s'' ([[Mitoxantrone]], [[Pixantrone]])
 
  
}}
+
  | group3 = [[Crosslinking of DNA]]<br />([[Cell-cycle nonspecific antineoplastic agents|CCNS]])
 +
  | list3 = {{Navbox|child
 +
    | evenodd = swap
  
 +
    | group1 = [[Alkylating antineoplastic agent|Alkylating]]
 +
    | list1 =
 +
* ''[[Nitrogen mustard]]s:'' [[Bendamustine]]<sup>#</sup>
 +
* [[Chlormethine]]
 +
* [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]]<sup>#</sup>
 +
* [[Trofosfamide]])
 +
* [[Chlorambucil]]<sup>#</sup> ([[Melphalan]]
 +
* [[Prednimustine]])
 +
* [[Uramustine]]
  
  | group3 = [[Crosslinking of DNA]]<BR>([[cell-cycle nonspecific antineoplastic agents|CCNS]])
+
* ''[[Nitrosourea]]s:'' [[Carmustine]]
  |  list3 = {{Navbox subgroup
+
* [[Fotemustine]]
| groupstyle = background-color: Plum
+
* [[Lomustine]] ([[Semustine]])
 +
* [[Nimustine]]
 +
* [[Ranimustine]]
 +
* [[Streptozotocin|Streptozocin]]
  
| group1 = [[Alkylating antineoplastic agent|Alkylating]]
+
* ''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]]
| list1  = ''[[Nitrogen mustard]]s:'' [[Mechlorethamine]]{{·}} [[Cyclophosphamide]] ([[Ifosfamide]], [[Trofosfamide]]){{·}} [[Chlorambucil]] ([[Melphalan]], [[Prednimustine]]){{·}} [[Bendamustine]]{{·}} [[Uramustine]]{{·}} [[Estramustine]]
+
* [[Treosulfan]])
  
''[[Nitrosourea]]s:'' [[Carmustine]]{{·}} [[Lomustine]] ([[Semustine]]){{·}} [[Fotemustine]]{{·}} [[Nimustine]]{{·}} [[Ranimustine]]{{·}} [[Streptozotocin|Streptozocin]]
+
* ''[[Aziridine]]s:'' [[Carboquone]]
 +
* [[Thiotepa]]
 +
* [[Triaziquone]]
 +
* [[Triethylenemelamine]]
  
''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]], [[Treosulfan]])
+
    | group2 = [[Platinum-based antineoplastic|Platinum-based]]
 +
    | list2 =
 +
* [[Carboplatin]]<sup>#</sup>
 +
* [[Cisplatin]]<sup>#</sup>
 +
* [[Dicycloplatin]]
 +
* [[Nedaplatin]]
 +
* [[Oxaliplatin]]<sup>#</sup>
 +
* [[Satraplatin]]
  
''[[Aziridine]]s:'' [[Carboquone]]{{·}} [[ThioTEPA]]{{·}} [[Triaziquone]]{{·}} [[Triethylenemelamine]]
+
    | group3 = [[Alkylating antineoplastic agent#Nonclassical|Nonclassical]]
 +
    | list3 =
 +
* [[Altretamine]]
 +
* ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>)
 +
* [[Mitobronitol]]
 +
* [[Pipobroman]]
 +
* ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup>
 +
* [[Temozolomide]])
  
| group2 = [[Alkylating_antineoplastic_agent#Alkylating-like|Alkylating-like]]
+
    | group4 = [[Intercalation (biochemistry)|Intercalation]]
| list2  = ''[[Platinum]]'' ([[Carboplatin]], [[Cisplatin]], [[Nedaplatin]], [[Oxaliplatin]], [[Triplatin tetranitrate]], [[Satraplatin]])
+
    | list4 =
 +
* [[Streptomyces]] ([[Actinomycin]]<sup>#</sup>
 +
* [[Bleomycin]]<sup>#</sup>
 +
* [[Mitomycins]]
 +
* [[Plicamycin]])
  
|group3  = [[Alkylating_antineoplastic_agent#Nonclassical|Nonclassical]]
+
  }}
|list3  = ''[[Hydrazine]]s'' ([[Procarbazine]]){{·}} ''[[Triazene]]s'' ([[Dacarbazine]], [[Temozolomide]]){{·}} [[Altretamine]]{{·}} [[Mitobronitol]]
+
  }}
  
|group4  = [[Intercalation (chemistry)|Intercalation]]
+
<!-- group3 omitted to preserve alternating striping -->
|list4  = [[Streptomyces]] ([[Actinomycin]], [[Bleomycin]], [[Mitomycin]], [[Plicamycin]])
 
  
}}
+
| group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]]
 +
| list4 =
 +
* [[Aminolevulinic acid]]&nbsp;/ [[Methyl aminolevulinate]]
 +
* [[Efaproxiral]]
 +
* [[Padeliporfin]]
 +
* ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]]
 +
* [[Talaporfin]]
 +
* [[Temoporfin]]
 +
* [[Verteporfin]])
  
 +
| group5 = Other
 +
| list5 = {{Navbox|child
  
}}
+
  | group1 = [[Enzyme inhibitor]]s
 +
  | list1 =
 +
* ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]<sup>§</sup>)
 +
* ''[[Cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Abemaciclib]]
 +
* [[Alvocidib]]<sup>†</sup>
 +
* [[Palbociclib]]
 +
* [[Ribociclib]]
 +
* [[Seliciclib]]<sup>†</sup>)
 +
* ''[[Proteasome inhibitor|PrI]]''
 +
** [[Bortezomib]]
 +
** [[Carfilzomib]]
 +
** [[Oprozomib]]
 +
** [[Ixazomib]]
 +
* ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]])
 +
* ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>)
 +
* ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]])
 +
* ''[[PARP inhibitor]]'' ([[Niraparib]]
 +
* [[Olaparib]]
 +
* [[Rucaparib]])
 +
* ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Belinostat]]
 +
* [[Panobinostat]]
 +
* [[Romidepsin]]
 +
* [[Vorinostat]])
 +
* ''[[Phosphoinositide 3-kinase inhibitor|PIKI]]'' ([[Alpelisib]]
 +
* [[Idelalisib]])
  
  | group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]]
+
  | group2 = [[Receptor antagonist]]s
  | list4 = [[D-Aminolevulinic acid|Aminolevulinic acid]]/[[Methyl aminolevulinate]]{{·}} [[Efaproxiral]]{{·}} ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]], [[Talaporfin]], [[Temoporfin]], [[Verteporfin]])
+
  | list2 =
 +
* ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]])
 +
* ''[[Retinoid X receptor]]'' ([[Bexarotene]])
 +
* ''[[Sex steroid]]'' ([[Testolactone]])
  
  | group5 = Other
+
  | group3 = Other/ungrouped
  | list5 = {{Navbox subgroup
+
  | list3 =
| groupstyle = background-color: Plum
+
* [[Amsacrine]]
 +
* [[Arsenic trioxide]]
 +
* ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]])
 +
* [[Celecoxib]]
 +
* [[Demecolcine]]
 +
* [[Elesclomol]]<sup>§</sup>
 +
* [[Elsamitrucin]]
 +
* [[Eribulin]]
 +
* [[Estramustine phosphate]]
 +
* [[Etoglucid]]
 +
* [[Lonidamine]]
 +
* [[Lucanthone]]
 +
* [[Mitoguazone]]
 +
* [[Mitotane]]
 +
* [[Oblimersen]]<sup>†</sup>
 +
* [[Omacetaxine mepesuccinate]]
 +
* [[Trabectedin]]
 +
* ''[[Retinoid]]s'' ([[Alitretinoin]]
 +
* [[Tretinoin]]<sup>#</sup>)
 +
* [[Venetoclax]]
  
| group1 = [[Enzyme inhibitor]]s
+
  }}
| list1 = ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]) {{·}} ''[[cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Alvocidib]], [[Seliciclib]]){{·}} ''[[Proteasome inhibitor|PrI]]'' ([[Bortezomib]]){{·}} ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]]){{·}} ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurine]]){{·}} ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]]){{·}} ''[[PARP inhibitor]]'' ([[Olaparib]]){{·}} ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Vorinostat]], [[Romidepsin]])
 
  
| group2 = [[Receptor antagonist]]s
+
| belowstyle = background: transparent; padding: 0px;
| list2  = ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]]){{·}} ''[[retinoid X receptor]]'' ([[Bexarotene]]){{·}} ''[[sex steroid]]'' ([[Testolactone]])
+
  | below = {{PharmNavFootnote}}
 
 
|group3 = Other/ungrouped
 
|list3  = [[Amsacrine]]{{·}} [[Trabectedin]]{{·}} ''[[retinoid]]s'' ([[Alitretinoin]], [[Tretinoin]]){{·}} [[Arsenic trioxide]]{{·}} ''[[Asparagine|asparagine depleter]]s'' ([[Asparaginase]]/[[Pegaspargase]]){{·}} [[Celecoxib]]{{·}} [[Demecolcine]]{{·}} [[Elesclomol]]{{·}} [[Elsamitrucin]]{{·}} [[Etoglucid]]{{·}} [[Lonidamine]]{{·}} [[Lucanthone]]{{·}} [[Mitoguazone]]{{·}} [[Mitotane]]{{·}} [[Oblimersen]]{{·}} ''[[mTOR inhibitor]]s'' ([[Everolimus]], [[Temsirolimus]])
 
}}
 
  
 
}}<noinclude>
 
}}<noinclude>
 
+
{{collapsible option}}
[[Category:Drug templates|{{PAGENAME}}]]
+
[[Category:Drug templates by ATC]]
[[Category:Oncology templates|{{PAGENAME}}]]
+
[[Category:Oncology templates]]
[[fr:Modèle:Agents chimiothérapeutiques]]
 
[[sl: Predloga: Citostatiki]]
 
[[th:แม่แบบ:Chemotherapeutic agents]]
 
 
</noinclude>
 
</noinclude>

Latest revision as of 14:51, 22 October 2020

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