Difference between revisions of "Template:Chemotherapeutic agents"

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{{Navbox
 
{{Navbox
| name = Intracellular chemotherapeutic agents
+
| name = Chemotherapeutic agents
|state = {{{state<includeonly>|collapsed</includeonly>}}}
+
| title = Intracellular [[Chemotherapy|chemotherapeutic agents]]&nbsp;/ [[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]])
| title = Intracellular [[Chemotherapy|chemotherapeutic agents]] / [[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]])
+
| state = {{{state<includeonly>|collapsed</includeonly>}}}
|listclass = hlist
+
| listclass = hlist
| groupstyle = background-color: #E5BFE5
 
  
  | group1 = [[Spindle poison|SP]]s/[[mitotic inhibitor|MI]]s<br />([[M phase]])
+
| group1 = [[Spindle poison|SP]]s/[[Mitotic inhibitor|MI]]s<br />([[M phase]])
  | list1 = {{Navbox subgroup
+
| list1 = {{Navbox|child
| groupstyle = background-color: #E5BFE5
 
  
| group1 = Block [[microtubule]] assembly
+
  | group1 = Block [[microtubule]] assembly
| list1 =
+
  | list1 =
 
* ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup>
 
* ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup>
 
* [[Vincristine]]<sup>#</sup>
 
* [[Vincristine]]<sup>#</sup>
 +
* [[Vindesine]]
 
* [[Vinflunine]]<sup>§</sup>
 
* [[Vinflunine]]<sup>§</sup>
* [[Vindesine]]
+
* [[Vinorelbine]]<sup>#</sup>)
* [[Vinorelbine]])
 
  
| group2 = Block microtubule disassembly
+
  | group2 = Block microtubule disassembly
| list2 =
+
  | list2 =
 
* ''[[Taxane]]s'' ([[Cabazitaxel]]
 
* ''[[Taxane]]s'' ([[Cabazitaxel]]
 
* [[Docetaxel]]<sup>#</sup>
 
* [[Docetaxel]]<sup>#</sup>
Line 28: Line 26:
 
* ''[[Epothilone]]s'' ([[Ixabepilone]])
 
* ''[[Epothilone]]s'' ([[Ixabepilone]])
  
}}
+
}}
 
 
  | group2 = [[DNA replication]]<br />inhibitor
 
  |  list2 = {{Navbox subgroup
 
  | groupstyle = background-color: #E5BFE5
 
  
| group1 = DNA precursors/<br />[[antimetabolite]]s<br />([[S phase]])
+
| group2 = [[DNA replication]]<br />inhibitor
| list1 = {{Navbox subgroup
+
| list2 = {{Navbox|child
  | groupstyle = background-color: #E5BFE5
 
  
 +
  | group1 = DNA precursors/<br />[[antimetabolite]]s<br />([[S phase]])
 +
  | list1 = {{Navbox|child
  
| group1 = [[Antifolate|Folic acid]]
+
    | group1 = [[Antifolate|Folic acid]]
| list1 =
+
    | list1 =
 
* ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]]
 
* ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]]
 
* [[Methotrexate]]<sup>#</sup>
 
* [[Methotrexate]]<sup>#</sup>
 
* [[Pemetrexed]]
 
* [[Pemetrexed]]
 
* [[Pralatrexate]])
 
* [[Pralatrexate]])
* ''[[Thymidylate synthase inhibitor]]'' ([[Raltitrexed]]
+
* ''[[Thymidylate synthase inhibitor]]'' ([[Pemetrexed]]
* [[Pemetrexed]])
+
* [[Raltitrexed]])
  
| group2 = [[Purine analogue|Purine]]
+
    | group2 = [[Purine analogue|Purine]]
| list2 =
+
    | list2 =
 
* ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]])
 
* ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]])
  
*''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]]
+
* ''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]]
 
* [[Clofarabine]]
 
* [[Clofarabine]]
 
* [[Fludarabine]])
 
* [[Fludarabine]])
* [[Nelarabine]]<br />
+
* [[Nelarabine]]
  
*''[[Thiopurine]]'' ([[Tioguanine|Thioguanine]]<sup>#</sup>
+
* ''[[Thiopurine]]'' ([[Mercaptopurine]]<sup>#</sup>
* [[Mercaptopurine]]<sup>#</sup>)
+
* [[Tioguanine]]<sup>#</sup>)
  
|group3 = [[Pyrimidine analogue|Pyrimidine]]  
+
    | group3 = [[Pyrimidine analogue|Pyrimidine]]
|list3   =
+
    | list3 =
* ''[[Thymidylate synthase inhibitor]]'' ([[Fluorouracil]]<sup>#</sup>
+
* ''[[Thymidylate synthase inhibitor]]'' ([[Capecitabine]]<sup>#</sup>
* [[Capecitabine]]
 
* [[Tegafur]] ([[Tegafur/gimeracil/oteracil|+gimeracil/oteracil]])
 
 
* [[Carmofur]]
 
* [[Carmofur]]
* [[Floxuridine]])
+
* [[Doxifluridine]]
 +
* [[Floxuridine]]
 +
* [[Fluorouracil]]<sup>#</sup>
 +
* [[Tegafur]] ([[Tegafur/gimeracil/oteracil|+gimeracil/oteracil]]))
  
*''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>)
+
* ''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>)
  
*''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]])
+
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]]<sup>#</sup>)
  
*''[[Hypomethylating agent]]'' ([[Azacitidine]]
+
* ''[[Hypomethylating agent]]'' ([[Azacitidine]]
 
* [[Decitabine]])
 
* [[Decitabine]])
  
|group4 = [[Deoxyribonucleotide]]
+
    | group4 = [[Deoxyribonucleotide]]
|list4   =
+
    | list4 =
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]])
+
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]]<sup>#</sup>)
  
}}
+
  }}
  
| group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]])
+
  | group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]])
| list2 = {{Navbox subgroup
+
  | list2 = {{Navbox|child
| groupstyle = background-color: #E5BFE5
 
  
| group1 = [[Topoisomerase_I#Inhibition|I]]
+
    | group1 = [[Type I topoisomerase#Inhibition|I]]
| list1 =
+
    | list1 =
* ''[[Camptotheca]]'' ([[Camptothecin]]
+
* ''[[Camptotheca]]'' ([[Belotecan]]
* [[Topotecan]]
+
* [[Camptothecin]]
* [[Irinotecan]]
+
* [[Cositecan]]<sup>†</sup>
 +
* [[Exatecan]]
 +
* [[Gimatecan]]
 +
* [[Irinotecan]]<sup>#</sup>
 +
* [[Lurtotecan]]<sup>‡</sup>
 
* [[Rubitecan]]<sup>‡</sup>
 
* [[Rubitecan]]<sup>‡</sup>
* [[Belotecan]])
+
* [[Silatecan]]<sup>§</sup>
 +
* [[Topotecan]])
  
| group2 = [[Topoisomerase_II#Inhibition|II]]
+
    | group2 = [[Type II topoisomerase#Inhibition|II]]
| list2 =
+
    | list2 =
 
* ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup>
 
* ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup>
 
* [[Teniposide]])
 
* [[Teniposide]])
  
| group3 = [[Topoisomerase_II#Inhibition|II]]+[[Intercalation (chemistry)|Intercalation]]
+
    | group3 = [[Type II topoisomerase#Inhibition|II]]+[[Intercalation (biochemistry)|Intercalation]]
| list3 =
+
    | list3 =
 
* ''[[Anthracycline]]s'' ([[Aclarubicin]]
 
* ''[[Anthracycline]]s'' ([[Aclarubicin]]
 +
* [[Amrubicin]]<sup>†</sup>
 
* [[Daunorubicin]]<sup>#</sup>
 
* [[Daunorubicin]]<sup>#</sup>
 
* [[Doxorubicin]]<sup>#</sup>
 
* [[Doxorubicin]]<sup>#</sup>
 
* [[Epirubicin]]
 
* [[Epirubicin]]
 
* [[Idarubicin]]
 
* [[Idarubicin]]
* [[Amrubicin]]<sup>†</sup>
 
 
* [[Pirarubicin]]
 
* [[Pirarubicin]]
 
* [[Valrubicin]]
 
* [[Valrubicin]]
 
* [[Zorubicin]])
 
* [[Zorubicin]])
 
* ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]]
 
* ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]]
 +
* [[Losoxantrone]]
 
* [[Pixantrone]])
 
* [[Pixantrone]])
  
}}
+
  }}
 
 
  
  | group3 = [[Crosslinking of DNA]]<br />([[cell-cycle nonspecific antineoplastic agents|CCNS]])
+
  | group3 = [[Crosslinking of DNA]]<br />([[Cell-cycle nonspecific antineoplastic agents|CCNS]])
  | list3 = {{Navbox subgroup
+
  | list3 = {{Navbox|child
| groupstyle = background-color: #E5BFE5
+
    | evenodd = swap
  
| group1 = [[Alkylating antineoplastic agent|Alkylating]]
+
    | group1 = [[Alkylating antineoplastic agent|Alkylating]]
| list1 =
+
    | list1 =
* ''[[Nitrogen mustard]]s:'' [[Mechlorethamine]]
+
* ''[[Nitrogen mustard]]s:'' [[Bendamustine]]<sup>#</sup>
* [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]]
+
* [[Chlormethine]]
 +
* [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]]<sup>#</sup>
 
* [[Trofosfamide]])
 
* [[Trofosfamide]])
 
* [[Chlorambucil]]<sup>#</sup> ([[Melphalan]]
 
* [[Chlorambucil]]<sup>#</sup> ([[Melphalan]]
 
* [[Prednimustine]])
 
* [[Prednimustine]])
* [[Bendamustine]]
 
 
* [[Uramustine]]
 
* [[Uramustine]]
* [[Estramustine]]
 
  
*''[[Nitrosourea]]s:'' [[Carmustine]]
+
* ''[[Nitrosourea]]s:'' [[Carmustine]]
 +
* [[Fotemustine]]
 
* [[Lomustine]] ([[Semustine]])
 
* [[Lomustine]] ([[Semustine]])
* [[Fotemustine]]
 
 
* [[Nimustine]]
 
* [[Nimustine]]
 
* [[Ranimustine]]
 
* [[Ranimustine]]
 
* [[Streptozotocin|Streptozocin]]
 
* [[Streptozotocin|Streptozocin]]
  
*''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]]
+
* ''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]]
 
* [[Treosulfan]])
 
* [[Treosulfan]])
  
*''[[Aziridine]]s:'' [[Carboquone]]
+
* ''[[Aziridine]]s:'' [[Carboquone]]
* [[ThioTEPA]]
+
* [[Thiotepa]]
 
* [[Triaziquone]]
 
* [[Triaziquone]]
 
* [[Triethylenemelamine]]
 
* [[Triethylenemelamine]]
  
| group2 = [[Platinum-based antineoplastic|Platinum-based]]
+
    | group2 = [[Platinum-based antineoplastic|Platinum-based]]
| list2 =
+
    | list2 =
* [[Carboplatin]]
+
* [[Carboplatin]]<sup>#</sup>
* [[Cisplatin]]
+
* [[Cisplatin]]<sup>#</sup>
 +
* [[Dicycloplatin]]
 
* [[Nedaplatin]]
 
* [[Nedaplatin]]
* [[Oxaliplatin]]
+
* [[Oxaliplatin]]<sup>#</sup>
 
* [[Satraplatin]]
 
* [[Satraplatin]]
  
|group3 = [[Alkylating_antineoplastic_agent#Nonclassical|Nonclassical]]
+
    | group3 = [[Alkylating antineoplastic agent#Nonclassical|Nonclassical]]
|list3   =
+
    | list3 =
 +
* [[Altretamine]]
 
* ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>)
 
* ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>)
 +
* [[Mitobronitol]]
 +
* [[Pipobroman]]
 
* ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup>
 
* ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup>
 
* [[Temozolomide]])
 
* [[Temozolomide]])
* [[Altretamine]]
 
* [[Mitobronitol]]
 
* [[Pipobroman]]
 
  
|group4 = [[Intercalation (chemistry)|Intercalation]]
+
    | group4 = [[Intercalation (biochemistry)|Intercalation]]
|list4   =
+
    | list4 =
 
* [[Streptomyces]] ([[Actinomycin]]<sup>#</sup>
 
* [[Streptomyces]] ([[Actinomycin]]<sup>#</sup>
 
* [[Bleomycin]]<sup>#</sup>
 
* [[Bleomycin]]<sup>#</sup>
* [[Mitomycin]]
+
* [[Mitomycins]]
 
* [[Plicamycin]])
 
* [[Plicamycin]])
  
}}
+
  }}
 
+
}}
  
}}
+
<!-- group3 omitted to preserve alternating striping -->
  
  | group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]]
+
| group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]]
  | list4 =
+
| list4 =
* [[D-Aminolevulinic acid|Aminolevulinic acid]] / [[Methyl aminolevulinate]]
+
* [[Aminolevulinic acid]]&nbsp;/ [[Methyl aminolevulinate]]
 
* [[Efaproxiral]]
 
* [[Efaproxiral]]
 +
* [[Padeliporfin]]
 
* ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]]
 
* ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]]
 
* [[Talaporfin]]
 
* [[Talaporfin]]
Line 183: Line 184:
 
* [[Verteporfin]])
 
* [[Verteporfin]])
  
  | group5 = Other
+
| group5 = Other
  | list5 = {{Navbox subgroup
+
| list5 = {{Navbox|child
| groupstyle = background-color: #E5BFE5
 
  
| group1 = [[Enzyme inhibitor]]s
+
  | group1 = [[Enzyme inhibitor]]s
| list1 =
+
  | list1 =
* ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]])  
+
* ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]<sup>§</sup>)
* ''[[cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Alvocidib]]<sup>†</sup>
+
* ''[[Cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Abemaciclib]]
 +
* [[Alvocidib]]<sup>†</sup>
 +
* [[Palbociclib]]
 +
* [[Ribociclib]]
 
* [[Seliciclib]]<sup>†</sup>)
 
* [[Seliciclib]]<sup>†</sup>)
* ''[[Proteasome inhibitor|PrI]]'' ([[Bortezomib]]
+
* ''[[Proteasome inhibitor|PrI]]''
* [[Carfilzomib]])
+
** [[Bortezomib]]
 +
** [[Carfilzomib]]
 +
** [[Oprozomib]]
 +
** [[Ixazomib]]
 
* ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]])
 
* ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]])
 
* ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>)
 
* ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>)
 
* ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]])
 
* ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]])
* ''[[PARP inhibitor]]'' ([[Olaparib]]<sup>§</sup>)
+
* ''[[PARP inhibitor]]'' ([[Niraparib]]
* ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Panobinostat]]
+
* [[Olaparib]]
* [[Vorinostat]]
+
* [[Rucaparib]])
* [[Romidepsin]])
+
* ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Belinostat]]
 +
* [[Panobinostat]]
 +
* [[Romidepsin]]
 +
* [[Vorinostat]])
 +
* ''[[Phosphoinositide 3-kinase inhibitor|PIKI]]'' ([[Alpelisib]]
 +
* [[Idelalisib]])
  
| group2 = [[Receptor antagonist]]s
+
  | group2 = [[Receptor antagonist]]s
| list2 =
+
  | list2 =
 
* ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]])
 
* ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]])
 
* ''[[Retinoid X receptor]]'' ([[Bexarotene]])
 
* ''[[Retinoid X receptor]]'' ([[Bexarotene]])
 
* ''[[Sex steroid]]'' ([[Testolactone]])
 
* ''[[Sex steroid]]'' ([[Testolactone]])
  
|group3 = Other/ungrouped
+
  | group3 = Other/ungrouped
|list3   =
+
  | list3 =
 
* [[Amsacrine]]
 
* [[Amsacrine]]
* [[Trabectedin]]
 
* ''[[Retinoid]]s'' ([[Alitretinoin]]
 
* [[Tretinoin]])
 
 
* [[Arsenic trioxide]]
 
* [[Arsenic trioxide]]
 
* ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]])
 
* ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]])
Line 220: Line 228:
 
* [[Elesclomol]]<sup>§</sup>
 
* [[Elesclomol]]<sup>§</sup>
 
* [[Elsamitrucin]]
 
* [[Elsamitrucin]]
 +
* [[Eribulin]]
 +
* [[Estramustine phosphate]]
 
* [[Etoglucid]]
 
* [[Etoglucid]]
 
* [[Lonidamine]]
 
* [[Lonidamine]]
Line 227: Line 237:
 
* [[Oblimersen]]<sup>†</sup>
 
* [[Oblimersen]]<sup>†</sup>
 
* [[Omacetaxine mepesuccinate]]
 
* [[Omacetaxine mepesuccinate]]
* [[Eribulin]]
+
* [[Trabectedin]]
}}
+
* ''[[Retinoid]]s'' ([[Alitretinoin]]
 +
* [[Tretinoin]]<sup>#</sup>)
 +
* [[Venetoclax]]
 +
 
 +
}}
  
| belowstyle = background: transparent; padding: 0px;
+
| belowstyle = background: transparent; padding: 0px;
| below = {{PharmNavFootnote}}{{Neoplasia navs}}
+
| below = {{PharmNavFootnote}}
  
 
}}<noinclude>
 
}}<noinclude>
 
{{collapsible option}}
 
{{collapsible option}}
[[Category:Antineoplastic drugs]]
+
[[Category:Drug templates by ATC]]
[[Category:Drug_templates by ATC]]
 
 
[[Category:Oncology templates]]
 
[[Category:Oncology templates]]
 
[[ru:Шаблон:АТХ код L01]]
 
 
</noinclude>
 
</noinclude>

Latest revision as of 14:51, 22 October 2020

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