Difference between revisions of "Template:Chemotherapeutic agents"
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{{Navbox | {{Navbox | ||
| − | | name | + | | name = Chemotherapeutic agents |
| − | + | | title = Intracellular [[Chemotherapy|chemotherapeutic agents]] / [[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]]) | |
| − | | title = Intracellular [[Chemotherapy|chemotherapeutic agents]] | + | | state = {{{state<includeonly>|collapsed</includeonly>}}} |
| − | | | + | | listclass = hlist |
| − | | | ||
| − | + | | group1 = [[Spindle poison|SP]]s/[[Mitotic inhibitor|MI]]s<br />([[M phase]]) | |
| − | + | | list1 = {{Navbox|child | |
| − | | | ||
| − | | group1 = Block [[microtubule]] assembly | + | | group1 = Block [[microtubule]] assembly |
| − | | list1 | + | | list1 = |
* ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup> | * ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup> | ||
* [[Vincristine]]<sup>#</sup> | * [[Vincristine]]<sup>#</sup> | ||
| + | * [[Vindesine]] | ||
* [[Vinflunine]]<sup>§</sup> | * [[Vinflunine]]<sup>§</sup> | ||
| − | + | * [[Vinorelbine]]<sup>#</sup>) | |
| − | * [[Vinorelbine]]) | ||
| − | | group2 = Block microtubule disassembly | + | | group2 = Block microtubule disassembly |
| − | | list2 | + | | list2 = |
* ''[[Taxane]]s'' ([[Cabazitaxel]] | * ''[[Taxane]]s'' ([[Cabazitaxel]] | ||
* [[Docetaxel]]<sup>#</sup> | * [[Docetaxel]]<sup>#</sup> | ||
| Line 28: | Line 26: | ||
* ''[[Epothilone]]s'' ([[Ixabepilone]]) | * ''[[Epothilone]]s'' ([[Ixabepilone]]) | ||
| − | }} | + | }} |
| − | |||
| − | |||
| − | |||
| − | |||
| − | | | + | | group2 = [[DNA replication]]<br />inhibitor |
| − | | | + | | list2 = {{Navbox|child |
| − | |||
| + | | group1 = DNA precursors/<br />[[antimetabolite]]s<br />([[S phase]]) | ||
| + | | list1 = {{Navbox|child | ||
| − | | group1 = [[Antifolate|Folic acid]] | + | | group1 = [[Antifolate|Folic acid]] |
| − | | list1 | + | | list1 = |
* ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]] | * ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]] | ||
* [[Methotrexate]]<sup>#</sup> | * [[Methotrexate]]<sup>#</sup> | ||
* [[Pemetrexed]] | * [[Pemetrexed]] | ||
* [[Pralatrexate]]) | * [[Pralatrexate]]) | ||
| − | * ''[[Thymidylate synthase inhibitor]]'' ([[ | + | * ''[[Thymidylate synthase inhibitor]]'' ([[Pemetrexed]] |
| − | * [[ | + | * [[Raltitrexed]]) |
| − | | group2 = [[Purine analogue|Purine]] | + | | group2 = [[Purine analogue|Purine]] |
| − | | list2 | + | | list2 = |
* ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]]) | * ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]]) | ||
| − | *''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]] | + | * ''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]] |
* [[Clofarabine]] | * [[Clofarabine]] | ||
* [[Fludarabine]]) | * [[Fludarabine]]) | ||
| − | * [[Nelarabine]] | + | * [[Nelarabine]] |
| − | *''[[Thiopurine]]'' ([[ | + | * ''[[Thiopurine]]'' ([[Mercaptopurine]]<sup>#</sup> |
| − | * [[ | + | * [[Tioguanine]]<sup>#</sup>) |
| − | |group3 | + | | group3 = [[Pyrimidine analogue|Pyrimidine]] |
| − | |list3 | + | | list3 = |
| − | * ''[[Thymidylate synthase inhibitor]]'' ([[ | + | * ''[[Thymidylate synthase inhibitor]]'' ([[Capecitabine]]<sup>#</sup> |
| − | |||
| − | |||
* [[Carmofur]] | * [[Carmofur]] | ||
| − | * [[Floxuridine]]) | + | * [[Doxifluridine]] |
| + | * [[Floxuridine]] | ||
| + | * [[Fluorouracil]]<sup>#</sup> | ||
| + | * [[Tegafur]] ([[Tegafur/gimeracil/oteracil|+gimeracil/oteracil]])) | ||
| − | *''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>) | + | * ''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>) |
| − | *''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]]) | + | * ''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]]<sup>#</sup>) |
| − | *''[[Hypomethylating agent]]'' ([[Azacitidine]] | + | * ''[[Hypomethylating agent]]'' ([[Azacitidine]] |
* [[Decitabine]]) | * [[Decitabine]]) | ||
| − | |group4 | + | | group4 = [[Deoxyribonucleotide]] |
| − | |list4 | + | | list4 = |
| − | * ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]]) | + | * ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]]<sup>#</sup>) |
| − | }} | + | }} |
| − | | group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]]) | + | | group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]]) |
| − | | list2 | + | | list2 = {{Navbox|child |
| − | | | ||
| − | | group1 = [[ | + | | group1 = [[Type I topoisomerase#Inhibition|I]] |
| − | | list1 | + | | list1 = |
| − | * ''[[Camptotheca]]'' ([[Camptothecin]] | + | * ''[[Camptotheca]]'' ([[Belotecan]] |
| − | * [[ | + | * [[Camptothecin]] |
| − | * [[Irinotecan]] | + | * [[Cositecan]]<sup>†</sup> |
| + | * [[Exatecan]] | ||
| + | * [[Gimatecan]] | ||
| + | * [[Irinotecan]]<sup>#</sup> | ||
| + | * [[Lurtotecan]]<sup>‡</sup> | ||
* [[Rubitecan]]<sup>‡</sup> | * [[Rubitecan]]<sup>‡</sup> | ||
| − | * [[ | + | * [[Silatecan]]<sup>§</sup> |
| + | * [[Topotecan]]) | ||
| − | | group2 = [[ | + | | group2 = [[Type II topoisomerase#Inhibition|II]] |
| − | | list2 | + | | list2 = |
* ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup> | * ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup> | ||
* [[Teniposide]]) | * [[Teniposide]]) | ||
| − | | group3 = [[ | + | | group3 = [[Type II topoisomerase#Inhibition|II]]+[[Intercalation (biochemistry)|Intercalation]] |
| − | | list3 | + | | list3 = |
* ''[[Anthracycline]]s'' ([[Aclarubicin]] | * ''[[Anthracycline]]s'' ([[Aclarubicin]] | ||
| + | * [[Amrubicin]]<sup>†</sup> | ||
* [[Daunorubicin]]<sup>#</sup> | * [[Daunorubicin]]<sup>#</sup> | ||
* [[Doxorubicin]]<sup>#</sup> | * [[Doxorubicin]]<sup>#</sup> | ||
* [[Epirubicin]] | * [[Epirubicin]] | ||
* [[Idarubicin]] | * [[Idarubicin]] | ||
| − | |||
* [[Pirarubicin]] | * [[Pirarubicin]] | ||
* [[Valrubicin]] | * [[Valrubicin]] | ||
* [[Zorubicin]]) | * [[Zorubicin]]) | ||
* ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]] | * ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]] | ||
| + | * [[Losoxantrone]] | ||
* [[Pixantrone]]) | * [[Pixantrone]]) | ||
| − | }} | + | }} |
| − | |||
| − | + | | group3 = [[Crosslinking of DNA]]<br />([[Cell-cycle nonspecific antineoplastic agents|CCNS]]) | |
| − | + | | list3 = {{Navbox|child | |
| − | | | + | | evenodd = swap |
| − | | group1 = [[Alkylating antineoplastic agent|Alkylating]] | + | | group1 = [[Alkylating antineoplastic agent|Alkylating]] |
| − | | list1 | + | | list1 = |
| − | * ''[[Nitrogen mustard]]s:'' [[ | + | * ''[[Nitrogen mustard]]s:'' [[Bendamustine]]<sup>#</sup> |
| − | * [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]] | + | * [[Chlormethine]] |
| + | * [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]]<sup>#</sup> | ||
* [[Trofosfamide]]) | * [[Trofosfamide]]) | ||
* [[Chlorambucil]]<sup>#</sup> ([[Melphalan]] | * [[Chlorambucil]]<sup>#</sup> ([[Melphalan]] | ||
* [[Prednimustine]]) | * [[Prednimustine]]) | ||
| − | |||
* [[Uramustine]] | * [[Uramustine]] | ||
| − | |||
| − | *''[[Nitrosourea]]s:'' [[Carmustine]] | + | * ''[[Nitrosourea]]s:'' [[Carmustine]] |
| + | * [[Fotemustine]] | ||
* [[Lomustine]] ([[Semustine]]) | * [[Lomustine]] ([[Semustine]]) | ||
| − | |||
* [[Nimustine]] | * [[Nimustine]] | ||
* [[Ranimustine]] | * [[Ranimustine]] | ||
* [[Streptozotocin|Streptozocin]] | * [[Streptozotocin|Streptozocin]] | ||
| − | *''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]] | + | * ''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]] |
* [[Treosulfan]]) | * [[Treosulfan]]) | ||
| − | *''[[Aziridine]]s:'' [[Carboquone]] | + | * ''[[Aziridine]]s:'' [[Carboquone]] |
| − | * [[ | + | * [[Thiotepa]] |
* [[Triaziquone]] | * [[Triaziquone]] | ||
* [[Triethylenemelamine]] | * [[Triethylenemelamine]] | ||
| − | | group2 = [[Platinum-based antineoplastic|Platinum-based]] | + | | group2 = [[Platinum-based antineoplastic|Platinum-based]] |
| − | | list2 | + | | list2 = |
| − | * [[Carboplatin]] | + | * [[Carboplatin]]<sup>#</sup> |
| − | * [[Cisplatin]] | + | * [[Cisplatin]]<sup>#</sup> |
| + | * [[Dicycloplatin]] | ||
* [[Nedaplatin]] | * [[Nedaplatin]] | ||
| − | * [[Oxaliplatin]] | + | * [[Oxaliplatin]]<sup>#</sup> |
* [[Satraplatin]] | * [[Satraplatin]] | ||
| − | |group3 | + | | group3 = [[Alkylating antineoplastic agent#Nonclassical|Nonclassical]] |
| − | |list3 | + | | list3 = |
| + | * [[Altretamine]] | ||
* ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>) | * ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>) | ||
| + | * [[Mitobronitol]] | ||
| + | * [[Pipobroman]] | ||
* ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup> | * ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup> | ||
* [[Temozolomide]]) | * [[Temozolomide]]) | ||
| − | |||
| − | |||
| − | |||
| − | |group4 | + | | group4 = [[Intercalation (biochemistry)|Intercalation]] |
| − | |list4 | + | | list4 = |
* [[Streptomyces]] ([[Actinomycin]]<sup>#</sup> | * [[Streptomyces]] ([[Actinomycin]]<sup>#</sup> | ||
* [[Bleomycin]]<sup>#</sup> | * [[Bleomycin]]<sup>#</sup> | ||
| − | * [[ | + | * [[Mitomycins]] |
* [[Plicamycin]]) | * [[Plicamycin]]) | ||
| − | }} | + | }} |
| − | + | }} | |
| − | + | <!-- group3 omitted to preserve alternating striping --> | |
| − | + | | group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]] | |
| − | + | | list4 = | |
| − | * [[ | + | * [[Aminolevulinic acid]] / [[Methyl aminolevulinate]] |
* [[Efaproxiral]] | * [[Efaproxiral]] | ||
| + | * [[Padeliporfin]] | ||
* ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]] | * ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]] | ||
* [[Talaporfin]] | * [[Talaporfin]] | ||
| Line 183: | Line 184: | ||
* [[Verteporfin]]) | * [[Verteporfin]]) | ||
| − | + | | group5 = Other | |
| − | + | | list5 = {{Navbox|child | |
| − | | | ||
| − | | group1 = [[Enzyme inhibitor]]s | + | | group1 = [[Enzyme inhibitor]]s |
| − | | list1 | + | | list1 = |
| − | * ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]) | + | * ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]<sup>§</sup>) |
| − | * ''[[ | + | * ''[[Cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Abemaciclib]] |
| + | * [[Alvocidib]]<sup>†</sup> | ||
| + | * [[Palbociclib]] | ||
| + | * [[Ribociclib]] | ||
* [[Seliciclib]]<sup>†</sup>) | * [[Seliciclib]]<sup>†</sup>) | ||
| − | * ''[[Proteasome inhibitor|PrI]]'' | + | * ''[[Proteasome inhibitor|PrI]]'' |
| − | * [[Carfilzomib]] | + | ** [[Bortezomib]] |
| + | ** [[Carfilzomib]] | ||
| + | ** [[Oprozomib]] | ||
| + | ** [[Ixazomib]] | ||
* ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]]) | * ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]]) | ||
* ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>) | * ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>) | ||
* ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]]) | * ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]]) | ||
| − | * ''[[PARP inhibitor]]'' ([[Olaparib]] | + | * ''[[PARP inhibitor]]'' ([[Niraparib]] |
| − | * ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Panobinostat]] | + | * [[Olaparib]] |
| − | * [[Vorinostat]] | + | * [[Rucaparib]]) |
| − | * [[ | + | * ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Belinostat]] |
| + | * [[Panobinostat]] | ||
| + | * [[Romidepsin]] | ||
| + | * [[Vorinostat]]) | ||
| + | * ''[[Phosphoinositide 3-kinase inhibitor|PIKI]]'' ([[Alpelisib]] | ||
| + | * [[Idelalisib]]) | ||
| − | | group2 = [[Receptor antagonist]]s | + | | group2 = [[Receptor antagonist]]s |
| − | | list2 | + | | list2 = |
* ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]]) | * ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]]) | ||
* ''[[Retinoid X receptor]]'' ([[Bexarotene]]) | * ''[[Retinoid X receptor]]'' ([[Bexarotene]]) | ||
* ''[[Sex steroid]]'' ([[Testolactone]]) | * ''[[Sex steroid]]'' ([[Testolactone]]) | ||
| − | |group3 | + | | group3 = Other/ungrouped |
| − | |list3 | + | | list3 = |
* [[Amsacrine]] | * [[Amsacrine]] | ||
| − | |||
| − | |||
| − | |||
* [[Arsenic trioxide]] | * [[Arsenic trioxide]] | ||
* ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]]) | * ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]]) | ||
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* [[Elesclomol]]<sup>§</sup> | * [[Elesclomol]]<sup>§</sup> | ||
* [[Elsamitrucin]] | * [[Elsamitrucin]] | ||
| + | * [[Eribulin]] | ||
| + | * [[Estramustine phosphate]] | ||
* [[Etoglucid]] | * [[Etoglucid]] | ||
* [[Lonidamine]] | * [[Lonidamine]] | ||
| Line 227: | Line 237: | ||
* [[Oblimersen]]<sup>†</sup> | * [[Oblimersen]]<sup>†</sup> | ||
* [[Omacetaxine mepesuccinate]] | * [[Omacetaxine mepesuccinate]] | ||
| − | * [[ | + | * [[Trabectedin]] |
| − | }} | + | * ''[[Retinoid]]s'' ([[Alitretinoin]] |
| + | * [[Tretinoin]]<sup>#</sup>) | ||
| + | * [[Venetoclax]] | ||
| + | |||
| + | }} | ||
| − | | belowstyle = background: transparent; padding: 0px; | + | | belowstyle = background: transparent; padding: 0px; |
| − | | below = {{PharmNavFootnote | + | | below = {{PharmNavFootnote}} |
}}<noinclude> | }}<noinclude> | ||
{{collapsible option}} | {{collapsible option}} | ||
| − | [[Category: | + | [[Category:Drug templates by ATC]] |
| − | |||
[[Category:Oncology templates]] | [[Category:Oncology templates]] | ||
| − | |||
| − | |||
</noinclude> | </noinclude> | ||
Latest revision as of 14:51, 22 October 2020
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