Difference between revisions of "Template:GHB receptor modulators"
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imported>Medgirl131 |
imported>JJMC89 bot III m (Moving Category:GHB to Category:Gamma-Hydroxybutyric acid per Wikipedia:Categories for discussion/Speedy) |
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{{Navbox | {{Navbox | ||
| − | | name = | + | | name = GHB receptor modulators |
| − | | title = [[ | + | | title = [[GHB receptor|{{abbr|GHB|γ-Hydroxybutyric acid}} receptor]] [[receptor modulator|modulator]]s |
| state = {{{state<includeonly>|collapsed</includeonly>}}} | | state = {{{state<includeonly>|collapsed</includeonly>}}} | ||
| − | | | + | | bodyclass = hlist |
| + | | groupstyle = text-align:center; | ||
| − | | group1 = | + | | group1 = [[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligand]]s)</small> |
| − | | list1 = {{Navbox subgroup | + | | list1 = {{Navbox|subgroup |
| + | | groupstyle = text-align:center; | ||
| + | | groupwidth = 4em; | ||
| − | | group1 = | + | | group1 = {{abbrlink|GHBR|GHB receptor}} |
| list1 = | | list1 = | ||
| − | * '''Agonists:''' ''Main site:'' [[1,4-Butanediol|1,4-BD]]<!--Prodrug--> | + | * '''Agonists:''' ''Main site:'' [[1,4-Butanediol|1,4-BD]]<!--Prodrug to GHB--> |
* [[3-Hydroxyphenylacetic acid|3-HPA]] | * [[3-Hydroxyphenylacetic acid|3-HPA]] | ||
| − | * [[Aceburic acid]]<!--Prodrug--> | + | * [[Aceburic acid|Aceburic acid (GHB acetate)]]<!--Prodrug to GHB--> |
| − | * [[1,4-Butanediol diacetate|BDDA (DABD)]]<!--Prodrug--> | + | * [[1,4-Butanediol diacetate|BDDA (DABD)]]<!--Prodrug to GHB--> |
| − | * [[Ethyl-4-acetoxybutanoate|EAB]]<!--Prodrug--> | + | * [[Ethyl-4-acetoxybutanoate|EAB]]<!--Prodrug to GHB--> |
| − | * [[γ-Butyrolactone|GBL]]<!--Prodrug--> | + | * [[γ-Butyrolactone|GBL]]<!--Prodrug to GHB--> |
| − | * [[γ-Crotonolactone|GCL | + | * [[γ-Crotonolactone|GCL]]<!--Prodrug to GHC--> |
* [[γ-Hydroxybutyric acid|GHB]] | * [[γ-Hydroxybutyric acid|GHB]] | ||
| − | * [[γ-Hydroxybutaldehyde|GHBAL]]<!--Prodrug--> | + | * [[γ-Hydroxybutaldehyde|GHBAL]]<!--Prodrug to GHB--> |
* [[γ-Hydroxyvaleric acid|GHV (4-methyl-GHB)]] | * [[γ-Hydroxyvaleric acid|GHV (4-methyl-GHB)]] | ||
| − | * [[γ-Valerolactone|GVL]]<!--Prodrug--> | + | * [[γ-Valerolactone|GVL]]<!--Prodrug to GHV--> |
* [[HOCHCA]] | * [[HOCHCA]] | ||
* [[HOCPCA]] | * [[HOCPCA]] | ||
| − | * [[Methyl-4-acetoxybutanoate|MAB]]<!--Prodrug--> | + | * [[Methyl-4-acetoxybutanoate|MAB]]<!--Prodrug to GHB--> |
* [[NCS-356]]<!--γ-(p-chlorobenzyl)-γ-hydroxybutanoic acid--> | * [[NCS-356]]<!--γ-(p-chlorobenzyl)-γ-hydroxybutanoic acid--> | ||
* [[NCS-435]]<!--γ-(p-methoxybenzyl)-γ-hydroxybutyric acid--> | * [[NCS-435]]<!--γ-(p-methoxybenzyl)-γ-hydroxybutyric acid--> | ||
| Line 37: | Line 40: | ||
* [[Monastrol]] | * [[Monastrol]] | ||
| − | * '''Antagonists:''' ''Main site:'' [[NCS-382]] | + | * '''Antagonists:''' ''Main site:'' [[Gabazine|Gabazine (SR-95531)]]<!--PMID: 22753476--> |
| + | * [[NCS-382]] | ||
* '''Unknown/unsorted:''' ''Main site:'' [[2-Hydroxyphenylacetic acid|2-HPA]] | * '''Unknown/unsorted:''' ''Main site:'' [[2-Hydroxyphenylacetic acid|2-HPA]] | ||
| Line 52: | Line 56: | ||
* [[δ-Hydroxyvaleric acid|DHV]] | * [[δ-Hydroxyvaleric acid|DHV]] | ||
* [[δ-Valerolactone|DVL]]<!--Prodrug--> | * [[δ-Valerolactone|DVL]]<!--Prodrug--> | ||
| − | |||
* [[γ-Thiobutyrolactone|GTBL]]<!--Prodrug--> | * [[γ-Thiobutyrolactone|GTBL]]<!--Prodrug--> | ||
* [[Levosulpiride]] | * [[Levosulpiride]] | ||
| Line 62: | Line 65: | ||
* [[UMB109]] | * [[UMB109]] | ||
* [[UMB119]] | * [[UMB119]] | ||
| + | |||
| + | | group2 = {{abbrlink|GABA<sub>B</sub>|γ-Aminobutyric acid B receptor}} | ||
| + | | list2 = | ||
| + | * See [[Template:GABA receptor modulators|here]] instead. | ||
}} | }} | ||
| − | | group2 = | + | | group2 = [[Neurotransmitter transporter|Transporter]]<br /><small>([[Reuptake inhibitor|blocker]]s)</small> |
| − | | list2 = {{Navbox subgroup | + | | list2 = {{Navbox|subgroup |
| + | | groupstyle = text-align:center; | ||
| + | | groupwidth = 4em; | ||
| − | | group1 = | + | | group1 = {{abbrlink|MCTs|Monocarboxylate transporters}}<!--Across BBB--> |
| list1 = | | list1 = | ||
* [[α-Ketoisocaproate]] | * [[α-Ketoisocaproate]] | ||
| Line 95: | Line 104: | ||
* [[Valproic acid]] | * [[Valproic acid]] | ||
| − | | group2 = | + | | group2 = {{abbrlink|SMCTs|Sodium-coupled monocarboxylate transporters}}<!--Across BBB--> |
| list2 = | | list2 = | ||
* [[Benzoic acid]] | * [[Benzoic acid]] | ||
| Line 111: | Line 120: | ||
* [[Salicyclic acid]] | * [[Salicyclic acid]] | ||
| − | | group3 = | + | | group3 = {{abbrlink|VIATT|Vesicular inhibitory amino acid transporter}} |
| list3 = | | list3 = | ||
* [[β-Alanine]] | * [[β-Alanine]] | ||
* [[Bafilomycin A1]] | * [[Bafilomycin A1]] | ||
* [[Butyric acid]] | * [[Butyric acid]] | ||
| − | * [[Chicago | + | * [[Chicago Sky Blue 6B]] |
| − | * [[Evans | + | * [[Evans Blue (dye)|Evans Blue]] |
* [[GABA]]<!--Competitive--> | * [[GABA]]<!--Competitive--> | ||
* [[Glycine]]<!--Competitive--> | * [[Glycine]]<!--Competitive--> | ||
| Line 127: | Line 136: | ||
}} | }} | ||
| − | | group3 = | + | | group3 = [[Enzyme]]<br /><small>([[Enzyme inhibitor|inhibitor]]s)</small> |
| − | | list3 = {{Navbox subgroup | + | | list3 = {{Navbox|subgroup |
| + | | groupstyle = text-align:center; | ||
| + | | groupwidth = 4em; | ||
| − | | group1 = | + | | group1 = {{abbrlink|SSR|Succinic semialdehyde reductase}} |
| list1 = | | list1 = | ||
* [[Quercetin]] | * [[Quercetin]] | ||
| − | | group2 = | + | | group2 = {{abbrlink|GHBDH|4-Hydroxybutyrate dehydrogenase}} |
| list2 = | | list2 = | ||
* [[α-Ketoisocaproic acid]] | * [[α-Ketoisocaproic acid]] | ||
| Line 144: | Line 155: | ||
* ''Enhancers:'' [[Glucuronic acid|<small>D</small>-Glucuronic acid]] | * ''Enhancers:'' [[Glucuronic acid|<small>D</small>-Glucuronic acid]] | ||
| − | | group3 = | + | | group3 = {{abbrlink|HOT|Hydroxyacid-oxoacid transhydrogenase}}<!--GHB transhydrogenase; mitochondrial enzyme--> |
| list3 = | | list3 = | ||
* [[Cyanide]] | * [[Cyanide]] | ||
* [[Phenanthroline]] | * [[Phenanthroline]] | ||
| − | | group4 = | + | | group4 = {{abbrlink|ADH|Alcohol dehydrogenase}} |
| list4 = | | list4 = | ||
* [[Cimetidine]] | * [[Cimetidine]] | ||
| Line 156: | Line 167: | ||
* [[Pyrazole]] | * [[Pyrazole]] | ||
| − | | group5 = | + | | group5 = {{abbrlink|ALDH|Aldehyde dehydrogenase}} |
| list5 = | | list5 = | ||
* [[Acetaldehyde]] | * [[Acetaldehyde]] | ||
| Line 166: | Line 177: | ||
}} | }} | ||
| − | | | + | | below = |
| − | + | ;See also | |
| − | + | : ''[[Template:Receptor modulators|Receptor/signaling modulators]]'' | |
| − | + | : ''[[Template:GABA receptor modulators|GABA receptor modulators]]'' | |
| − | + | : ''[[Template:Glutamate receptor modulators|Glutamate receptor modulators]]'' | |
| − | + | : ''[[Template:Glycine receptor modulators|Glycine receptor modulators]]'' | |
| − | |||
| − | |||
}}<noinclude> | }}<noinclude> | ||
{{collapsible option}} | {{collapsible option}} | ||
[[Category:Drug templates by receptor, channel, or pump]] | [[Category:Drug templates by receptor, channel, or pump]] | ||
| − | [[Category: | + | [[Category:Gamma-Hydroxybutyric acid]] |
</noinclude> | </noinclude> | ||
Latest revision as of 07:24, 25 June 2020
Initial visibility: currently defaults to autocollapse
To set this template's initial visibility, the |state= parameter may be used:
|state=collapsed:{{GHB receptor modulators|state=collapsed}}to show the template collapsed, i.e., hidden apart from its title bar|state=expanded:{{GHB receptor modulators|state=expanded}}to show the template expanded, i.e., fully visible|state=autocollapse:{{GHB receptor modulators|state=autocollapse}}
If the |state= parameter in the template on this page is not set, the template's initial visibility is taken from the |default= parameter in the Collapsible option template. For the template on this page, that currently evaluates to autocollapse.