imported>Anomie |
imported>Medgirl131 |
| (31 intermediate revisions by 8 users not shown) |
| Line 1: |
Line 1: |
| − | <noinclude>{{toobig|date=December 2015}}</noinclude>
| + | {{Navboxes |
| − | {{Navbox
| + | | title = [[Glutamate receptor]] [[receptor modulator|modulator]]s |
| − | | name = Glutamatergics
| + | | titlestyle = background:#ccccff |
| − | | title = [[Glutamate]]rgics | |
| | | state = {{{state<includeonly>|collapsed</includeonly>}}} | | | state = {{{state<includeonly>|collapsed</includeonly>}}} |
| − | | listclass = hlist | + | | list1 = |
| − | | groupstyle = text-align:center;
| + | {{Ionotropic glutamate receptor modulators}} |
| − | | + | {{Metabotropic glutamate receptor modulators}} |
| − | | group1 = [[Receptor (biochemistry)|Receptor]]<br />{{smaller|([[Ligand (biochemistry)|ligands]])}}
| |
| − | | list1 = {{Navbox|child
| |
| − | | groupstyle = text-align:center;
| |
| − | | |
| − | | group1 = [[AMPA receptor|AMPA]]
| |
| − | | list1 =
| |
| − | * '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Fluorowillardiine]]
| |
| − | * [[Acromelic acid|Acromelic acid (acromelate)]]
| |
| − | * [[AMPA]]
| |
| − | * [[β-N-Oxalylamino-L-Alanine|BOAA]]
| |
| − | * [[Domoic acid]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[Proline]]
| |
| − | * [[Quisqualic acid]]
| |
| − | * [[Willardiine]]; ''Positive allosteric modulators:'' [[Aniracetam]]
| |
| − | * [[Cyclothiazide]]
| |
| − | * [[CX-516]]
| |
| − | * [[CX-546]]
| |
| − | * [[CX-614]]
| |
| − | * [[Farampator|Farampator (CX-691, Org 24448)]]
| |
| − | * [[CX-717]]
| |
| − | * [[CX-1739]]
| |
| − | * [[CX-1942]]
| |
| − | * [[Diazoxide]]
| |
| − | * [[Hydrochlorothiazide|Hydrochlorothiazide (HCTZ)]]
| |
| − | * [[IDRA-21]]
| |
| − | * [[LY-392,098]]
| |
| − | * [[LY-404,187]]
| |
| − | * [[LY-451,646]]
| |
| − | * [[LY-503,430]]
| |
| − | * [[Mibampator|Mibampator (LY-451,395)]]
| |
| − | * [[Org 26576]]
| |
| − | * [[Oxiracetam]]
| |
| − | * [[PEPA (drug)|PEPA]]
| |
| − | * [[PF-04958242]]
| |
| − | * [[Piracetam]]
| |
| − | * [[Pramiracetam]]
| |
| − | * [[S-18986]]
| |
| − | * [[Sunifiram]]
| |
| − | * [[Unifiram]]
| |
| − | * '''Antagonists:''' [[ACEA-1011]]
| |
| − | * [[ATPO]]
| |
| − | * [[Becampanel]]
| |
| − | * [[Caroverine]]
| |
| − | * [[CNQX]]
| |
| − | * [[Dasolampanel]]
| |
| − | * [[DNQX]]
| |
| − | * [[Fanapanel|Fanapanel (MPQX)]]
| |
| − | * [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]
| |
| − | * [[GYKI-52466]]
| |
| − | * [[Kynurenic acid]]
| |
| − | * [[Kynurenine]]<!--As a prodrug of kynurenic acid-->
| |
| − | * [[Licostinel|Licostinel (ACEA-1021)]]
| |
| − | * [[NBQX]]
| |
| − | * [[PNQX]]
| |
| − | * [[Selurampanel]]
| |
| − | * [[Tezampanel]]
| |
| − | * [[Theanine]]
| |
| − | * [[Topiramate]]
| |
| − | * [[YM90K]]
| |
| − | * [[Zonampanel]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])
| |
| − | * [[Cyclopropane]]
| |
| − | * [[Enflurane]]
| |
| − | * [[Ethanol]]
| |
| − | * [[Evans blue]]
| |
| − | * [[GYKI-53,655]]
| |
| − | * [[Halothane]]
| |
| − | * [[Irampanel]]
| |
| − | * [[Isoflurane]]
| |
| − | * [[Perampanel]]
| |
| − | * [[Pregnenolone sulfate]]
| |
| − | * [[Talampanel]]
| |
| − | | |
| − | | group2 = [[NMDA receptor|NMDA]]
| |
| − | | list2 =
| |
| − | * '''Agonists:''' ''Glutamate/active site agonists:'' [[2-Amino-2-(3-hydroxy-5-methylisoxazol-4-yl)acetic acid|AMAA]]
| |
| − | * [[Aspartate]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Homocysteic acid|Homocysteic acid (<small>L</small>-HCA)]]
| |
| − | * [[Homoquinolinic acid]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[N-Methyl-D-aspartic acid|NMDA]]
| |
| − | * [[Proline]]
| |
| − | * [[Quinolinic acid]]
| |
| − | * [[Tetrazolylglycine]]
| |
| − | * [[Theanine]]; ''Glycine site agonists:'' [[β-Fluoro-D-alanine|β-Fluoro-<small>D</small>-alanine]]
| |
| − | * [[ACBD (drug)|ACBD]]
| |
| − | * [[1-Aminocyclopropanecarboxylic acid|ACC (ACPC)]]
| |
| − | * [[ACPD]]
| |
| − | * [[AK-51 (drug)|AK-51]]
| |
| − | * [[Carboxycyclopropylglycine|CCG]]
| |
| − | * [[Alanine|<small>D</small>-Alanine]]
| |
| − | * [[Cycloserine|<small>D</small>-Cycloserine]]
| |
| − | * [[Serine|<small>D</small>-Serine]]
| |
| − | * [[N-(3,3-Diphenylpropyl)glycinamide|DHPG]]
| |
| − | * [[Glycine]]
| |
| − | * [[HA-966]]
| |
| − | * [[L-687,414]]
| |
| − | * [[Alanine|<small>L</small>-Alanine]]
| |
| − | * [[Serine|<small>L</small>-Serine]]
| |
| − | * [[Milacemide]]
| |
| − | * [[Neboglamine]]
| |
| − | * [[NRX-1074]]
| |
| − | * [[Rapastinel|Rapastinel (GLYX-13)]]
| |
| − | * [[Sarcosine]]; ''Polyamine site agonists:'' [[Spermidine]]
| |
| − | * [[Spermine]]
| |
| − | * '''Antagonists:''' ''Competitive antagonists:'' [[AP5|AP5 (APV)]]
| |
| − | * [[AP-7 (drug)|AP7]]
| |
| − | * [[CGP-37849]]
| |
| − | * [[CGP-39551]]
| |
| − | * [[CGP-39653]]
| |
| − | * [[CGP-40116]]
| |
| − | * [[CGS-19755]]
| |
| − | * [[3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid|CPP]]
| |
| − | * [[LY-233,053]]
| |
| − | * [[LY-235,959]]
| |
| − | * [[LY-274,614]]
| |
| − | * [[MDL-100,453]]
| |
| − | * [[Midafotel|Midafotel (d-CPPene)]]
| |
| − | * [[NPC-12,626]]
| |
| − | * [[NPC-17,742]]
| |
| − | * [[PBPD]]
| |
| − | * [[PEAQX]]
| |
| − | * [[Perzinfotel]]
| |
| − | * [[cis-1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid|PPDA]]
| |
| − | * [[SDZ-220581]]
| |
| − | * [[Selfotel]]; ''Noncompetitive antagonists:'' [[ARR-15,896]]
| |
| − | * [[Caroverine]]
| |
| − | * [[Dexanabinol]]
| |
| − | * [[FPL-12495]]
| |
| − | * [[FR-115,427]]
| |
| − | * [[Hodgkinsine]]
| |
| − | * [[Magnesium]]
| |
| − | * [[MDL-27,266]]
| |
| − | * [[NPS-1506]]
| |
| − | * [[Psychotridine]]
| |
| − | * [[Zinc]]; ''Uncompetitive pore blockers:'' [[2-MDP]]
| |
| − | * [[3-HO-PCP]]
| |
| − | * [[3-MeO-PCE]]
| |
| − | * [[3-MeO-PCMo]]
| |
| − | * [[3-MeO-PCP]]
| |
| − | * [[4-MeO-PCP]]
| |
| − | * [[8a-Phenyldecahydroquinoline|8A-PDHQ]]
| |
| − | * [[18-Methoxycoronaridine|18-MC]]
| |
| − | * [[Alpha-Endopsychosin|α-Endopsychosin]]
| |
| − | * [[Alaproclate]]
| |
| − | * [[Amantadine]]
| |
| − | * [[Aptiganel]]
| |
| − | * [[Arketamine]]
| |
| − | * [[ARL-12,495]]
| |
| − | * [[ARL-15,896-AR]]
| |
| − | * [[ARL-16,247]]
| |
| − | * [[Budipine]]
| |
| − | * [[Conaridine]]
| |
| − | * [[Delucemine]]
| |
| − | * [[Dexoxadrol]]
| |
| − | * [[Dextrallorphan]]
| |
| − | * [[Dieticyclidine]]
| |
| − | * [[Diphenidine]]
| |
| − | * [[Dizocilpine]]
| |
| − | * [[Ephenidine]]
| |
| − | * [[Esketamine]]
| |
| − | * [[Etoxadrol]]
| |
| − | * [[Eticyclidine]]
| |
| − | * [[Fluorolintane]]
| |
| − | * [[Gacyclidine]]
| |
| − | * [[Ibogaine]]
| |
| − | * [[Ibogamine]]
| |
| − | * [[Indantadol]]
| |
| − | * [[Ketamine]]
| |
| − | * [[Ketobemidone]]
| |
| − | * [[Lanicemine]]
| |
| − | * [[Loperamide]]
| |
| − | * [[Memantine]]
| |
| − | * [[Methadone]] ([[Levomethadone]])
| |
| − | * [[Methorphan]] ([[Dextromethorphan]]
| |
| − | * [[Levomethorphan]])
| |
| − | * [[Methoxetamine]]
| |
| − | * [[Methoxphenidine]]
| |
| − | * [[Milnacipran]]
| |
| − | * [[Morphanol]] ([[Dextrorphan]]
| |
| − | * [[Levorphanol]])
| |
| − | * [[NEFA (drug)|NEFA]]
| |
| − | * [[Neramexane]]
| |
| − | * [[Nitromemantine]]
| |
| − | * [[Nitrous oxide]]
| |
| − | * [[Noribogaine]]
| |
| − | * [[Norketamine]]
| |
| − | * [[Orphenadrine]]
| |
| − | * [[PCPr]]
| |
| − | * [[Pethidine|Pethidine (meperidine)]]
| |
| − | * [[Phencyclamine]]
| |
| − | * [[Phencyclidine]]
| |
| − | * [[Propoxyphene]]
| |
| − | * [[Remacemide]]
| |
| − | * [[Rhynchophylline]]
| |
| − | * [[Rimantadine]]
| |
| − | * [[Rolicyclidine]]
| |
| − | * [[Sabeluzole]]
| |
| − | * [[Tabernanthine]]
| |
| − | * [[Tenocyclidine]]
| |
| − | * [[Tiletamine]]
| |
| − | * [[Tramadol]]
| |
| − | * [[Xenon]]; ''Glycine site antagonists:'' [[4-Chlorokynurenine|4-Cl-KYN (AV-101)]]
| |
| − | * [[5,7-Dichlorokynurenic acid|5,7-DCKA]]
| |
| − | * [[7-Chlorokynurenate|7-CKA]]
| |
| − | * [[1-Aminocyclopropane-1-carboxylic acid|ACC]]
| |
| − | * [[ACEA-1011]]
| |
| − | * [[ACEA-1328]]
| |
| − | * [[AV-101]]
| |
| − | * [[Carisoprodol]]
| |
| − | * [[CGP-39653]]
| |
| − | * [[CNQX]]
| |
| − | * [[DNQX]]
| |
| − | * [[Felbamate]]
| |
| − | * [[Gavestinel]]
| |
| − | * [[GV-196,771]]
| |
| − | * [[Kynurenic acid]]
| |
| − | * [[Kynurenine]]<!--As a prodrug of kynurenic acid-->
| |
| − | * [[L-689,560]]
| |
| − | * [[L-701,324]]
| |
| − | * [[Licostinel|Licostinel (ACEA-1021)]]
| |
| − | * [[LU-73,068]]
| |
| − | * [[MDL-105,519]]
| |
| − | * [[Meprobamate]]
| |
| − | * [[MRZ 2/576]]
| |
| − | * [[PNQX]]
| |
| − | * [[ZD-9379]]; ''NR2B subunit antagonists:'' [[Besonprodil]]
| |
| − | * [[CERC-301|CERC-301 (MK-0657)]]
| |
| − | * [[CO-101,244|CO-101,244 (PD-174,494)]]
| |
| − | * [[Eliprodil]]
| |
| − | * [[Haloperidol]]
| |
| − | * [[Ifenprodil]]
| |
| − | * [[Isoxsuprine]]
| |
| − | * [[Nylidrin]]
| |
| − | * [[Ro8-4304]]
| |
| − | * [[Ro25-6981]]
| |
| − | * [[Traxoprodil]]; ''Polyamine site antagonists:'' [[Arcaine]]
| |
| − | * [[Co 101676]]
| |
| − | * [[1,3-Diaminopropane|Diaminopropane]]
| |
| − | * [[Diethylenetriamine]]
| |
| − | * [[Huperzine A]]
| |
| − | * [[Putrescine]]
| |
| − | * [[Ro 25-6981]]; ''Unclassified/unsorted antagonists:'' [[Bumetanide]]
| |
| − | * [[Chloroform]]
| |
| − | * [[Cyclopropane]]
| |
| − | * [[D-α-Aminoadipate|<small>D</small>-αAA]]
| |
| − | * [[Diethyl ether]]
| |
| − | * [[Enflurane]]
| |
| − | * [[Ethanol]]
| |
| − | * [[Flufenamic acid]]
| |
| − | * [[Flupirtine]]
| |
| − | * [[Furosemide]]
| |
| − | * [[Halothane]]
| |
| − | * [[Isoflurane]]
| |
| − | * [[Metaphit]]<!--Irreversible-->
| |
| − | * [[Methoxyflurane]]
| |
| − | * [[Niflumic acid]]
| |
| − | * [[Piretanide]]
| |
| − | * [[Toluene]]
| |
| − | * [[Transcrocetin]] ([[saffron]])
| |
| − | * [[1,1,1-Trichloroethane|Trichloroethane]]
| |
| − | * [[2,2,2-Trichloroethanol|Trichloroethanol]]
| |
| − | * [[Trichloroethylene]]
| |
| − | * [[Xylene]]
| |
| − | | |
| − | | group3 = [[Kainate receptor|Kainate]]
| |
| − | | list3 =
| |
| − | * '''Agonists:''' ''Glutamate/active site agonists:'' [[5-Bromowillardiine]]
| |
| − | * [[5-Iodowillardiine]]
| |
| − | * [[Acromelic acid|Acromelic acid (acromelate)]]
| |
| − | * [[AMPA]]
| |
| − | * [[ATPA]]
| |
| − | * [[Domoic acid]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[Kainic acid]]
| |
| − | * [[LY-339,434]]
| |
| − | * [[Proline]]
| |
| − | * [[Quisqualic acid]]
| |
| − | * [[SYM-2081]]; ''Positive allosteric modulators:'' [[Cyclothiazide]]
| |
| − | * [[Diazoxide]]
| |
| − | * [[Enflurane]]
| |
| − | * [[Halothane]]
| |
| − | * [[Isoflurane]]
| |
| − | * '''Antagonists:''' [[ACEA-1011]]
| |
| − | * [[CNQX]]
| |
| − | * [[Dasolampanel]]
| |
| − | * [[DNQX]]
| |
| − | * [[gamma-D-Glutamylaminomethylsulfonic acid|GAMS]]
| |
| − | * [[Kynurenic acid]]
| |
| − | * [[Licostinel|Licostinel (ACEA-1021)]]
| |
| − | * [[LY-382,884]]
| |
| − | * [[NBQX]]
| |
| − | * [[NS102]]
| |
| − | * [[Selurampanel]]
| |
| − | * [[Tezampanel]]
| |
| − | * [[Theanine]]
| |
| − | * [[Topiramate]]
| |
| − | * [[UBP-302]]; ''Negative allosteric modulators:'' [[Barbiturates]] (e.g., [[pentobarbital]], [[sodium thiopental]])
| |
| − | * [[Enflurane]]
| |
| − | * [[Ethanol]]
| |
| − | * [[Evans blue]]
| |
| − | * [[NS-3763]]
| |
| − | * [[Pregnenolone sulfate]]
| |
| − | | |
| − | | group4 = [[Metabotropic glutamate receptor 1|mGlu<sub>1</sub>]]
| |
| − | | list4 =
| |
| − | * '''Agonists:''' [[ACPD]]
| |
| − | * [[Dihydroxyphenylglycine|DHPG]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[Quisqualic acid]]
| |
| − | * [[Ro01-6128]]
| |
| − | * [[Ro67-4853]]
| |
| − | * [[Ro67-7476]]
| |
| − | * [[VU-71]]
| |
| − | * '''Antagonists:''' [[BAY 36-7620]]
| |
| − | * [[CPCCOEt]]
| |
| − | * [[Cyclothiazide]]
| |
| − | * [[LY-367,385]]
| |
| − | * [[LY-456,236]]
| |
| − | * [[MCPG]]
| |
| − | * [[NPS-2390]]
| |
| − | | |
| − | | group5 = [[Metabotropic glutamate receptor 2|mGlu<sub>2</sub>]]
| |
| − | | list5 =
| |
| − | * '''Agonists:''' [[Biphenylindanone A|BINA]]
| |
| − | * [[CBiPES]]
| |
| − | * [[DCG-IV]]
| |
| − | * [[Eglumegad]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[LY-379,268]]
| |
| − | * [[LY-404,039|LY-404,039 (pomaglumetad)]]
| |
| − | * [[LY-487,379]]
| |
| − | * [[LY-566,332]]
| |
| − | * [[MGS-0028]]
| |
| − | * [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]
| |
| − | * [[Talaglumetad]]; ''Positive allosteric modulators:'' [[JNJ-40411813|JNJ-40411813 (ADX-71149)]]
| |
| − | * '''Antagonists:''' [[APICA (drug)|APICA]]
| |
| − | * [[CECXG]]
| |
| − | * [[EGLU]]
| |
| − | * [[HYDIA]]
| |
| − | * [[LY-307,452]]
| |
| − | * [[LY-341,495]]
| |
| − | * [[MCPG]]
| |
| − | * [[MGS-0039]]
| |
| − | * [[PCCG-4]]; ''Negative allosteric modulators:'' [[Decoglurant]]
| |
| − | * [[RO4491533]]
| |
| − | | |
| − | | group6 = [[Metabotropic glutamate receptor 3|mGlu<sub>3</sub>]]
| |
| − | | list6 =
| |
| − | * '''Agonists:''' [[CBiPES]]
| |
| − | * [[DCG-IV]]
| |
| − | * [[Eglumegad]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[LY-379,268]]
| |
| − | * [[LY-404,039|LY-404,039 (pomaglumetad)]]
| |
| − | * [[LY-487,379]]
| |
| − | * [[MGS-0028]]
| |
| − | * [[Pomaglumetad methionil|Pomaglumetad methionil (LY-2140023)]]
| |
| − | * [[Talaglumetad]]
| |
| − | * '''Antagonists:''' [[APICA (drug)|APICA]]
| |
| − | * [[CECXG]]
| |
| − | * [[EGLU]]
| |
| − | * [[HYDIA]]
| |
| − | * [[LY-307,452]]
| |
| − | * [[LY-341,495]]
| |
| − | * [[MCPG]]
| |
| − | * [[MGS-0039]]; ''Negative allosteric modulators:'' [[Decoglurant]]
| |
| − | * [[RO4491533]]
| |
| − | | |
| − | | group7 = [[Metabotropic glutamate receptor 4|mGlu<sub>4</sub>]]
| |
| − | | list7 =
| |
| − | * '''Agonists:''' [[Glutamate]]
| |
| − | * [[L-AP4|<small>L</small>-AP4]]
| |
| − | * [[PHCCC]]
| |
| − | * [[VU-001,171]]
| |
| − | * [[VU-0155,041]]; ''Positive allosteric modulators:'' [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]
| |
| − | * '''Antagonists:''' [[CPPG]]
| |
| − | * [[MAP4 (drug)|MAP4]]
| |
| − | * [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]
| |
| − | * [[MSOP (drug)|MSOP]]
| |
| − | * [[MTPG]]
| |
| − | * [[UBP-1112]]
| |
| − | | |
| − | | group8 = [[Metabotropic glutamate receptor 5|mGlu<sub>5</sub>]]
| |
| − | | list8 =
| |
| − | * '''Agonists:''' [[ACPD]]
| |
| − | * [[ADX-47273]]
| |
| − | * [[CDPPB]]
| |
| − | * [[Chlorohydroxyphenylglycine|CHPG]]
| |
| − | * [[1-(3-fluorophenyl)-N-((3-fluorophenyl)methylideneamino)methanimine|DFB]]
| |
| − | * [[Dihydroxyphenylglycine|DHPG]]
| |
| − | * [[Glutamate]]
| |
| − | * [[Ibotenic acid]]
| |
| − | * [[Quisqualic acid]]
| |
| − | * [[VU-1545]]
| |
| − | * '''Antagonists:''' [[CTEP]]
| |
| − | * [[DMeOB]]
| |
| − | * [[LY-344,545]]
| |
| − | * [[Mavoglurant]]
| |
| − | * [[MCPG]]
| |
| − | * [[NPS-2390]]
| |
| − | * [[Remeglurant]]
| |
| − | * [[SIB-1757]]
| |
| − | * [[SIB-1893]]; ''Negative allosteric modulators:'' [[Basimglurant]]
| |
| − | * [[Dipraglurant]]
| |
| − | * [[Fenobam]]
| |
| − | * [[GRN-529]]
| |
| − | * [[2-Methyl-6-(phenylethynyl)pyridine|MPEP]]
| |
| − | * [[MTEP]]
| |
| − | * [[Raseglurant]]
| |
| − | | |
| − | | group9 = [[Metabotropic glutamate receptor 6|mGlu<sub>6</sub>]]
| |
| − | | list9 =
| |
| − | * '''Agonists:''' [[Glutamate]]
| |
| − | * [[L-AP4|<small>L</small>-AP4]]
| |
| − | * '''Antagonists:''' [[CPPG]]
| |
| − | * [[MAP4 (drug)|MAP4]]
| |
| − | * [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]
| |
| − | * [[MSOP (drug)|MSOP]]
| |
| − | * [[MTPG]]
| |
| − | * [[UBP-1112]]
| |
| − | | |
| − | | group10 = [[Metabotropic glutamate receptor 7|mGlu<sub>7</sub>]]
| |
| − | | list10 =
| |
| − | * '''Agonists:''' [[AMN082]]
| |
| − | * [[Glutamate]]
| |
| − | * [[L-AP4|<small>L</small>-AP4]]
| |
| − | * '''Antagonists:''' [[CPPG]]
| |
| − | * [[MAP4 (drug)|MAP4]]
| |
| − | * [[MMPIP]]
| |
| − | * [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]
| |
| − | * [[MSOP (drug)|MSOP]]
| |
| − | * [[MTPG]]
| |
| − | * [[UBP-1112]]
| |
| − | | |
| − | | group11 = [[Metabotropic glutamate receptor 8|mGlu<sub>8</sub>]]
| |
| − | | list11 =
| |
| − | * '''Agonists:''' [[DCPG]]
| |
| − | * [[Glutamate]]
| |
| − | * [[L-AP4|<small>L</small>-AP4]]
| |
| − | * '''Antagonists:''' [[CPPG]]
| |
| − | * [[MAP4 (drug)|MAP4]]
| |
| − | * [[Alpha-methyl-4-phosphonophenylglycine|MPPG]]
| |
| − | * [[MSOP (drug)|MSOP]]
| |
| − | * [[MTPG]]
| |
| − | * [[UBP-1112]]
| |
| − | | |
| − | }}
| |
| − | | |
| − | | group2 = [[Neurotransmitter transporter|Transporter]]<br />{{smaller|([[Excitatory amino acid reuptake inhibitor|blockers]])}}
| |
| − | | list2 = {{Navbox|child
| |
| − | | groupstyle = text-align:center;
| |
| − | | |
| − | | group1 = [[Glutamate transporter|EAATs]]
| |
| − | | list1 =
| |
| − | * [[Amphetamine]]
| |
| − | * [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive-->
| |
| − | * [[cis-1-Aminocyclobutane-1,3-dicarboxylic acid|''cis''-ACBD]]
| |
| − | * [[Dihydrokainic acid|DHKA]]
| |
| − | * [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive-->
| |
| − | * [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-4-carboxylic acid|HIP-A]]
| |
| − | * [[3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo(3,4-d)isoxazole-6-carboxylic acid|HIP-B]]
| |
| − | * [[Kainic acid]]
| |
| − | * [[3-Hydroxyaspartic acid|<small>L</small>-(-)-''threo''-3-Hydroxyaspartic acid]]
| |
| − | * [[L-α-Aminoadipate|<small>L</small>-αAA]]
| |
| − | * [[(2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine|<small>L</small>-CCG-III ((2S,3S,4R)-CCG)]]
| |
| − | * [[L-Serine-O-sulphate|<small>L</small>-Serine-O-sulphate (SOS)]]
| |
| − | * [[L-trans-Pyrrolidine-2,4-dicarboxylic acid|<small>L</small>-''trans''-2,4-PDC]]
| |
| − | * [[L-anti-endo-3,4-Methanopyrrolidinedicarboxylic acid|MPDC]]
| |
| − | * [[SYM-2081]]
| |
| − | * [[threo-β-Benzyloxyaspartic acid|TBOA]]
| |
| − | * [[TFB-TBOA]]
| |
| − | * [[Theanine]]
| |
| − | * [[threo-3-Methylglutamic acid|''threo''-3-Methylglutamic acid]]
| |
| − | * [[UCPH-101]]
| |
| − | * [[WAY-213,613]]
| |
| − | | |
| − | | group2 = [[Vesicular glutamate transporters|vGluTs]]
| |
| − | | list2 =
| |
| − | * [[4-Methylene-L-glutamate|4-Methylene-<small>L</small>-glutamate]]
| |
| − | * [[6-(4'-Phenylstyryl)-quinoline-2,4-dicarboxylic acid|6-(4'-Phenylstyryl)-QDC]]
| |
| − | * [[6-Biphenyl-4-yl-quinoline-2,4-dicarboxylic acid|6-Biphenyl-4-yl-QDC]]
| |
| − | * [[7-Chlorokynurenic acid|7-CKA]]
| |
| − | * [[Acid red 114]]
| |
| − | * [[Amido black 10B|Amido black 10B (naphthol blue black)]]
| |
| − | * [[Bafilomycin A1]]
| |
| − | * [[Benzopurpurin 4B]]
| |
| − | * [[Bumetamide]]
| |
| − | * [[Chicago sky blue 6B]]
| |
| − | * [[Aspartic acid|Aspartic acid (aspartate)]]<!--Competitive-->
| |
| − | * [[DIDS]]
| |
| − | * [[Direct blue 71]]
| |
| − | * [[Erythro-4-methyl-L-glutamic acid|Erythro-4-methyl-<small>L</small>-glutamic acid]]
| |
| − | * [[Evans blue]]
| |
| − | * [[Furosemide]]
| |
| − | * [[Glutamic acid|Glutamic acid (glutamate)]]<!--Competitive-->
| |
| − | * [[Kynurenic acid]]
| |
| − | * [[Nigericin]]
| |
| − | * [[5-Nitro-2-(3-phenylpropylamino)benzoic acid|NPPB (N144)]]
| |
| − | * [[Ponceau SS]]
| |
| − | * [[Reactive blue 2]]
| |
| − | * [[Rose bengal]]
| |
| − | * [[4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid|SITS]]
| |
| − | * [[Trans-1-aminocyclopentane-1,3-dicarboxylic acid|''trans''-ACDP]]
| |
| − | * [[Trypan blue]]
| |
| − | * [[Valinomycin]]
| |
| − | * [[Xanthurenic acid]]
| |
| − | | |
| − | }}
| |
| − | | |
| − | | group3 = [[Enzyme]]<br />{{smaller|([[Enzyme inhibitor|inhibitors]])}}
| |
| − | | list3 = {{Navbox|child
| |
| − | | groupstyle = text-align:center;
| |
| − | | |
| − | | group1 = [[Glutaminase|GAH]]
| |
| − | | list1 =
| |
| − | * [[BPTES]]
| |
| − | * [[CB-839]]
| |
| − | * [[6-Diazo-5-oxo-L-norleucine|DON]]
| |
| − | | |
| − | | group2 = [[Aspartate aminotransferase|AST]]
| |
| − | | list2 =
| |
| − | * [[2-Amino-3-butenoic acid]]
| |
| − | * [[Aminooxyacetic acid|AAOA]]
| |
| − | * [[L-2-Amino-4-methoxy-trans-3-butenoic acid|AMB]]
| |
| − | * [[β-DL-Methylene-aspartate|β-{{smaller|DL}}-Methylene-aspartate]]
| |
| − | * [[Hydrazinosuccinate]]
| |
| − | | |
| − | | group3 = [[Alanine aminotransferase|ALT]]
| |
| − | | list3 =
| |
| − | * [[β-Chloro-L-alanine|β-Chloro-{{smaller|L}}-alanine]]
| |
| − | * [[L-Cycloserine|{{smaller|L}}-Cycloserine]]
| |
| − | * [[Propargylglycine]]
| |
| − | | |
| − | | group4 = [[Glutamate dehydrogenase|GDH]]
| |
| − | | list4 =
| |
| − | * [[Aminooxyacetic acid|AAOA]]
| |
| − | * [[Bithionol]]
| |
| − | * [[Chloroquine]]
| |
| − | * [[Epigallocatechin-3-gallate|EGCG]]
| |
| − | * [[Guanosine-5'-triphosphate|GTP]]
| |
| − | * [[GW5074]]
| |
| − | * [[Hexachlorophene]]
| |
| − | * [[Hydroxylamine]]
| |
| − | * [[Palmitoyl-coenzyme A|Palmitoyl-CoA]]
| |
| − | * [[Pyridoxal phosphate]]
| |
| − | | |
| − | | group5 = [[Glutamine synthetase|GS]]
| |
| − | | list5 =
| |
| − | * [[2-Aminoadipic acid]]
| |
| − | * [[JFD01307SC]]
| |
| − | * [[Methionine sulfoximine]]
| |
| − | * [[Phosphinothricin|Phosphinothricin (glufosinate)]]
| |
| − | | |
| − | | group6 = [[Glutamate decarboxylase|GAD]]
| |
| − | | list6 =
| |
| − | * [[3-Mercaptopropionic acid]]
| |
| − | * [[Aminooxyacetic acid|AAOA]]
| |
| − | * [[L-Allylglycine|<small>L</small>-Allylglycine]]
| |
| − | * [[Semicarbazide]]
| |
| − | | |
| − | }}
| |
| − | | |
| − | | group4 = Others
| |
| − | | list4 =
| |
| − | * '''Precursors:''' [[γ-Hydroxybutyric acid|GHB]]<!--PMID: 10381791-->
| |
| − | * [[Glutamine|<small>L</small>-Glutamine]]
| |
| − | * '''Cofactors:''' [[α-Ketoglutaric acid]]
| |
| − | * [[Iron]]
| |
| − | * [[Sulfur]]
| |
| − | * [[Vitamin B2|Vitamin B<sub>2</sub>]]
| |
| − | * [[Vitamin B3|Vitamin B<sub>3</sub>]]
| |
| − | * '''Others:''' [[Acamprosate]]
| |
| − | * [[Cysteine]]
| |
| − | * [[Cytidine]]
| |
| − | * [[Cytisine]]
| |
| − | * [[Glutathione]]
| |
| − | * [[Glutathione disulfide]]
| |
| − | * [[Minocycline]]
| |
| − | * [[N-Acetylcysteine]]
| |
| − | * [[Riluzole]]
| |
| − | * [[S-Nitrosoglutathione]]
| |
| − | * [[Tianeptine]]
| |
| − | | |
| − | | below = '''''See also:''' [[Template:GABAergics|GABAergics]] • [[Template:GHBergics|GHBergics]] • [[Template:Glycinergics|Glycinergics]]''
| |
| − | | |
| | }}<noinclude> | | }}<noinclude> |
| | {{collapsible option}} | | {{collapsible option}} |
| | [[Category:Drug templates by receptor, channel, or pump]] | | [[Category:Drug templates by receptor, channel, or pump]] |
| | </noinclude> | | </noinclude> |
