Difference between revisions of "Template:Histamine receptor modulators"

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{{Navbox
 
{{Navbox
| name = Histaminergics
+
| name = Histamine receptor modulators
| title = [[Histaminergic]]s
+
| title = [[Histamine receptor]] [[receptor modulator|modulator]]s
| state = {{{state|autocollapse}}}
+
| state = {{{state<includeonly>|collapsed</includeonly>}}}
 +
| border = {{{border|}}}
 
| listclass = hlist
 
| listclass = hlist
| groupstyle = background-color: LightYellow
+
| groupstyle = text-align: center;
  
   | group1 = <center>[[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligand]]s)</small></center>
+
   | group1 = [[Histamine H1 receptor|H<sub>1</sub>]]
  |  list1 = {{Navbox subgroup
+
  | list1 =
  | groupstyle = background-color: LightYellow
+
* '''Agonists:''' [[2-Pyridylethylamine]]
 
 
    | group1 = [[Histamine H1 receptor|H<sub>1</sub>]]
 
    | list1 =
 
* '''Agonists''': [[2-Pyridylethylamine]]
 
 
* [[Betahistine]]
 
* [[Betahistine]]
 
* [[Histamine]]
 
* [[Histamine]]
 
* [[Histamine trifluoromethyl toluidide|HTMT]]
 
* [[Histamine trifluoromethyl toluidide|HTMT]]
* [[UR-AK49]]<br/>'''Antagonists''': ''1st generation'': [[4-Methyldiphenhydramine]]
+
* [[L-Histidine|{{smaller|L}}-Histidine]]<!--Precursor-->
 +
* [[UR-AK49]]
 +
 
 +
* '''Antagonists:''' ''First-generation:'' [[4-Methyldiphenhydramine]]
 
* [[Alimemazine]]
 
* [[Alimemazine]]
 
* [[Antazoline]]
 
* [[Antazoline]]
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* [[Clobenzepam]]
 
* [[Clobenzepam]]
 
* [[Clocinizine]]
 
* [[Clocinizine]]
 +
* [[Cloperastine]]
 
* [[Cyclizine]]
 
* [[Cyclizine]]
 
* [[Cyproheptadine]]
 
* [[Cyproheptadine]]
 
* [[Dacemazine]]
 
* [[Dacemazine]]
 +
* [[Decloxizine]]
 
* [[Deptropine]]
 
* [[Deptropine]]
 
* [[Dexbrompheniramine]]
 
* [[Dexbrompheniramine]]
Line 52: Line 54:
 
* [[Etybenzatropine|Etybenzatropine (ethylbenztropine)]]
 
* [[Etybenzatropine|Etybenzatropine (ethylbenztropine)]]
 
* [[Etymemazine]]
 
* [[Etymemazine]]
 +
* [[Fenethazine]]
 
* [[Flunarizine]]
 
* [[Flunarizine]]
 
* [[Histapyrrodine]]
 
* [[Histapyrrodine]]
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* [[Isothipendyl]]
 
* [[Isothipendyl]]
 
* [[Meclozine]]
 
* [[Meclozine]]
 +
* [[Medrylamine]]
 
* [[Mepyramine|Mepyramine (pyrilamine)]]
 
* [[Mepyramine|Mepyramine (pyrilamine)]]
 
* [[Mequitazine]]
 
* [[Mequitazine]]
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* [[Methdilazine]]
 
* [[Methdilazine]]
 
* [[Moxastine]]
 
* [[Moxastine]]
* [[Niaprazine]]
 
 
* [[Orphenadrine]]
 
* [[Orphenadrine]]
 
* [[Oxatomide]]
 
* [[Oxatomide]]
 
* [[Oxomemazine]]
 
* [[Oxomemazine]]
 +
* [[Perlapine]]
 
* [[Phenindamine]]
 
* [[Phenindamine]]
 
* [[Pheniramine]]
 
* [[Pheniramine]]
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* [[Tolpropamine]]
 
* [[Tolpropamine]]
 
* [[Tripelennamine]]
 
* [[Tripelennamine]]
* [[Triprolidine]]; ''2nd generation'': [[Acrivastine]]
+
* [[Triprolidine]]
 +
 
 +
* ''Second/third-generation:'' [[Acrivastine]]
 
* [[Alinastine]]
 
* [[Alinastine]]
 
* [[Astemizole]]
 
* [[Astemizole]]
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* [[Clemizole]]
 
* [[Clemizole]]
 
* [[Clobenztropine]]
 
* [[Clobenztropine]]
 +
* [[Desloratadine]]
 
* [[Dorastine]]
 
* [[Dorastine]]
 
* [[Ebastine]]
 
* [[Ebastine]]
 +
* [[Efletirizine]]
 
* [[Emedastine]]
 
* [[Emedastine]]
 
* [[Epinastine]]
 
* [[Epinastine]]
 +
* [[Fexofenadine]]
 
* [[Flezelastine]]
 
* [[Flezelastine]]
 
* [[Ketotifen]]
 
* [[Ketotifen]]
 
* [[Latrepirdine]]
 
* [[Latrepirdine]]
 
* [[Levocabastine]]
 
* [[Levocabastine]]
 +
* [[Levocetirizine]]
 
* [[Linetastine]]
 
* [[Linetastine]]
 
* [[Loratadine]]
 
* [[Loratadine]]
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* [[Olopatadine]]
 
* [[Olopatadine]]
 
* [[Perastine]]
 
* [[Perastine]]
 +
* [[Pibaxizine]]
 
* [[Piclopastine]]
 
* [[Piclopastine]]
 +
* [[Quifenadine|Quifenadine (phencarol)]]
 
* [[Rocastine]]
 
* [[Rocastine]]
 
* [[Rupatadine]]
 
* [[Rupatadine]]
 
* [[Setastine]]
 
* [[Setastine]]
 +
* [[Sequifenadine|Sequifenadine (bicarphen)]]
 
* [[Talastine]]
 
* [[Talastine]]
 
* [[Temelastine]]
 
* [[Temelastine]]
 
* [[Terfenadine]]
 
* [[Terfenadine]]
* [[Zepastine]]; ''3rd generation'': [[Desloratadine]]
+
* [[Vapitadine]]
* [[Fexofenadine]]
+
* [[Zepastine]]
* [[Levocetirizine]]; ''Ungrouped'': [[Belarizine]]
+
 
* [[Efletirizine]]
+
* ''Others:'' [[Atypical antipsychotic]]s (e.g., [[aripiprazole]], [[asenapine]], [[brexpiprazole]], [[brilaroxazine]], [[clozapine]], [[iloperidone]], [[olanzapine]], [[paliperidone]], [[quetiapine]], [[risperidone]], [[ziprasidone]], [[zotepine]])
 +
* [[Phenylpiperazine]] [[antidepressant]]s (e.g., [[hydroxynefazodone]], [[nefazodone]], [[trazodone]], [[triazoledione]])
 +
* [[Tetracyclic antidepressant]]s (e.g., [[amoxapine]], [[loxapine]], [[maprotiline]], [[mianserin]], [[mirtazapine]], [[oxaprotiline]])
 +
* [[Tricyclic antidepressant]]s (e.g., [[amitriptyline]], [[butriptyline]], [[clomipramine]], [[desipramine]], [[Dosulepin|dosulepin (dothiepin)]], [[doxepin]], [[imipramine]], [[iprindole]], [[lofepramine]], [[nortriptyline]], [[protriptyline]], [[trimipramine]])
 +
* [[Typical antipsychotic]]s (e.g., [[chlorpromazine]], [[flupenthixol]], [[fluphenazine]], [[loxapine]], [[perphenazine]], [[prochlorperazine]], [[thioridazine]], [[thiothixene]])
 +
 
 +
* ''Unknown/unsorted:'' [[Azanator]]  
 +
* [[Belarizine]]
 
* [[Elbanizine]]
 
* [[Elbanizine]]
 
* [[Flotrenizine]]
 
* [[Flotrenizine]]
* [[Medrylamine]]
+
* [[GSK1004723]]
 
* [[Napactadine]]
 
* [[Napactadine]]
* [[Pibaxizine]]
 
 
* [[Tagorizine]]
 
* [[Tagorizine]]
 
* [[Trelnarizine]]
 
* [[Trelnarizine]]
 
* [[Trenizine]]
 
* [[Trenizine]]
* [[Vapitadine]]; ''Miscellaneous'': [[Tricyclic antidepressant]]s ([[amitriptyline]],
 
* [[doxepin]],
 
* [[trimipramine]], etc)
 
* [[Tetracyclic antidepressant]]s ([[mianserin]],
 
* [[mirtazapine]], etc)
 
* [[Typical antipsychotic]]s ([[chlorpromazine]],
 
* [[thioridazine]], etc)
 
* [[Atypical antipsychotic]]s ([[clozapine]],
 
* [[olanzapine]],
 
* [[quetiapine]], etc)
 
  
    | group2 = [[Histamine H2 receptor|H<sub>2</sub>]]
+
  | group2 = [[Histamine H2 receptor|H<sub>2</sub>]]
    | list2 =
+
  | list2 =
* '''Agonists''': [[Amthamine]]
+
* '''Agonists:''' [[Amthamine]]
 
* [[Betazole]]
 
* [[Betazole]]
 
* [[Dimaprit]]
 
* [[Dimaprit]]
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* [[Histamine trifluoromethyl toluidide|HTMT]]
 
* [[Histamine trifluoromethyl toluidide|HTMT]]
 
* [[Impromidine]]
 
* [[Impromidine]]
* [[UR-AK49]]<br/>'''Antagonists''': [[Bisfentidine]]
+
* [[L-Histidine|{{smaller|L}}-Histidine]]<!--Precursor-->
 +
* [[UR-AK49]]
 +
 
 +
* '''Antagonists:''' [[Bisfentidine]]
 
* [[Burimamide]]
 
* [[Burimamide]]
 
* [[Cimetidine]]
 
* [[Cimetidine]]
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* [[Etintidine]]
 
* [[Etintidine]]
 
* [[Famotidine]]
 
* [[Famotidine]]
 +
* [[Isolamtidine]]
 
* [[Lafutidine]]
 
* [[Lafutidine]]
 
* [[Lamtidine]]
 
* [[Lamtidine]]
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* [[Venritidine]]
 
* [[Venritidine]]
 
* [[Xaltidine]]
 
* [[Xaltidine]]
 +
* [[Zolantidine]]
  
    | group3 = [[Histamine H3 receptor|H<sub>3</sub>]]
+
  | group3 = [[Histamine H3 receptor|H<sub>3</sub>]]
    | list3 =
+
  | list3 =
* '''Agonists''': [[alpha-Methylhistamine|α-Methylhistamine]]
+
* '''Agonists:''' [[alpha-Methylhistamine|α-Methylhistamine]]
 
* [[Cipralisant]]
 
* [[Cipralisant]]
 
* [[Histamine]]
 
* [[Histamine]]
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* [[Immepip]]
 
* [[Immepip]]
 
* [[Immethridine]]
 
* [[Immethridine]]
 +
* [[L-Histidine|{{smaller|L}}-Histidine]]<!--Precursor-->
 
* [[Methimepip]]
 
* [[Methimepip]]
* [[Proxyfan]]<br/>'''Antagonists''': [[A-349,821]]
+
* [[Proxyfan]]
* [[A-423,579]]
+
 
 +
* '''Antagonists:''' [[A-349821]]
 +
* [[A-423579]]
 
* [[ABT-239]]
 
* [[ABT-239]]
 
* [[ABT-652]]
 
* [[ABT-652]]
 
* [[AZD5213]]
 
* [[AZD5213]]
 +
* [[Bavisant]]
 
* [[Betahistine]]
 
* [[Betahistine]]
 
* [[Burimamide]]
 
* [[Burimamide]]
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* [[Clobenpropit]]
 
* [[Clobenpropit]]
 
* [[Conessine]]
 
* [[Conessine]]
* [[GSK-189,254]]
+
* [[Enerisant]]
 +
* [[GSK-189254]]
 
* [[Impentamine]]
 
* [[Impentamine]]
 
* [[Iodophenpropit]]
 
* [[Iodophenpropit]]
 
* [[Irdabisant]]
 
* [[Irdabisant]]
 
* [[JNJ-5207852]]
 
* [[JNJ-5207852]]
* [[MK-0249]]
 
 
* [[NNC 38-1049]]
 
* [[NNC 38-1049]]
 
* [[PF-03654746]]
 
* [[PF-03654746]]
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* [[VUF-5681]]
 
* [[VUF-5681]]
  
    | group4 = [[Histamine H4 receptor|H<sub>4</sub>]]
+
  | group4 = [[Histamine H4 receptor|H<sub>4</sub>]]
    | list4 =
+
  | list4 =
* '''Agonists''': [[4-Methylhistamine]]
+
* '''Agonists:''' [[4-Methylhistamine]]
 
* [[alpha-Methylhistamine|α-Methylhistamine]]
 
* [[alpha-Methylhistamine|α-Methylhistamine]]
 
* [[Histamine]]
 
* [[Histamine]]
* [[VUF-8430]]<br/>'''Antagonists''': [[JNJ-7777120]]
+
* [[L-Histidine|{{smaller|L}}-Histidine]]<!--Precursor-->
* [[JNJ-38518168]]
+
* [[OUP-16]]
 +
* [[VUF-8430]]
 +
 
 +
* '''Antagonists:''' [[JNJ-7777120]]
 +
* [[Mianserin]]
 +
* [[Seliforant]]
 
* [[Thioperamide]]
 
* [[Thioperamide]]
 +
* [[Toreforant]]
 
* [[VUF-6002]]
 
* [[VUF-6002]]
  
  }}
+
  | below = '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]] [[Template:Monoamine metabolism modulators|Monoamine metabolism modulators]] [[Template:Monoamine reuptake inhibitors|Monoamine reuptake inhibitors]]''
 
 
  | group2 = <center>[[Neurotransmitter transporter|Transporter]]<br /><small>([[Reuptake inhibitor|inhibitor]]s)</small></center>
 
  | list2 = {{Navbox subgroup
 
  | groupstyle = background-color: LightYellow
 
 
 
    | group1 = [[Vesicular monoamine transporter 2|VMAT2]]
 
    | list1  = {{Navbox subgroup
 
    | groupstyle = background-color: LightYellow
 
 
 
      | group1 = <center><small>[[TAAR1]] inactive</small></center>
 
      | list1  =
 
* [[Ibogaine]]
 
* [[Reserpine]]
 
* [[Tetrabenazine]]
 
      | group2 = <center><small>[[TAAR1]] active</small></center>
 
      | list2  =<!-- there are many others in this category... these are just the articles that have a suitable citation which states that they inhibit VMAT2 -->
 
* [[Amphetamine]] (reserpine binding site)
 
* [[Methamphetamine]] (tetrabenazine binding site)
 
* [[MDMA|3,4-Methylenedioxymethamphetamine]]
 
* [[Phenethylamine]]
 
    }}
 
  }}
 
 
 
  | group3 = <center>[[Enzyme]]<br /><small>([[Enzyme inhibitor|inhibitor]]s)</small></center>
 
  | list3  = {{Navbox subgroup
 
  | groupstyle = background-color: LightYellow
 
 
 
    | group1 = [[Histidine decarboxylase|HDC]]
 
    | list1  =
 
* [[(+)-Catechin|Catechin]]
 
* [[Meciadanol]]
 
* [[Naringenin]]
 
* [[Tritoqualine]]
 
 
 
    | group2 = [[Histamine N-methyltransferase|HNMT]]
 
    | list2  =
 
* [[Amodiaquine]]
 
* [[Diphenhydramine]]
 
* [[Harmaline]]
 
* [[Metoprine]]
 
* [[Quinacrine]]
 
* [[SKF-91,488]]
 
* [[Tacrine]]
 
 
 
    | group3 = [[Diamine oxidase|DAO]]
 
    | list3  =
 
* [[Aminoguanidine]]
 
 
 
  }}
 
 
 
  | group4 = <center>Others</center>
 
  |  list4 = {{Navbox subgroup
 
  | groupstyle = background-color: LightYellow
 
 
 
    | group1 = [[Endogenous]]
 
    | list1  =
 
* [[Histamine]]; ''Precursors:'' [[L-Histidine|<small>L</small>-Histidine]]; ''Cofactors:'' [[Vitamin B6|Vitamin B<sub>6</sub>]]
 
 
 
  }}
 
  
}}<noinclude>
+
}}
 +
<noinclude>
 
{{collapsible option}}
 
{{collapsible option}}
 
[[Category:Drug templates by receptor, channel, or pump]]
 
[[Category:Drug templates by receptor, channel, or pump]]
 
</noinclude>
 
</noinclude>

Latest revision as of 20:13, 11 June 2020

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