Difference between revisions of "Template:Cell wall disruptive antibiotics"
Jump to navigation
Jump to search
(Oops, accidentally pressed Entert) |
({{Navbox with collapsible sections}} because template's rhs so bulky (perhaps further collapsible sections within, e.g. the Beta-lactams section)) |
||
| Line 1: | Line 1: | ||
| − | {{Navbox | + | {{Navbox with collapsible sections |
| − | | name = Cell wall disruptive antibiotics | + | |name = Cell wall disruptive antibiotics |
| − | | title = [[Antibiotic|Antibacterials]]: [[cell envelope antibiotic]]s ([[ATC code J01#J01C Beta-lactam antibacterials|J01C]]-[[ | + | |title = [[Antibiotic|Antibacterials]] : [[cell envelope antibiotic]]s ([[ATC code J01#J01C Beta-lactam antibacterials|J01C]]-[[ATC code J01#J01D Other beta-lactam antibacterials|J01D]]) |
| − | | groupstyle = background:PowderBlue; | + | |groupstyle = background:PowderBlue; line-height:1.2em; padding:0.2em; |
| − | |||
| − | |group1 | + | |group1 = Internal to membrane<br/>{{nobold|(inhibiting [[peptidoglycan]] subunit synthesis and transport)}} |
| − | |list1 | + | |list1 = <div> |
| + | {{nowrap|[[N-Acetylmuramic acid|NAM]] synthesis inhibitors ([[Fosfomycin]])}}{{·}} | ||
| + | {{nowrap|[[D-alanine-D-alanine ligase|DADAL]]/[[alanine racemase|AR]] inhibitors ([[Cycloserine]])}}{{·}} | ||
| + | {{nowrap|[[bactoprenol]] inhibitors ([[Bacitracin]])}} | ||
| + | </div> | ||
| − | | group2 = [[Glycopeptide antibiotic|Glycopeptide]]/ | + | |group2 = [[Glycopeptide antibiotic|Glycopeptide]]<br/>{{nobold|(inhibiting [[Peptidoglycan glycosyltransferase|PG]] chain elongation)}} |
| − | | | + | |list2 = <div> |
| + | [[Vancomycin]]{{smallsup|1}} ([[Oritavancin]]{{·}} | ||
| + | [[Telavancin]]){{·}} | ||
| + | [[Teicoplanin]] ([[Dalbavancin]]){{·}} | ||
| + | [[Ramoplanin]] | ||
| + | </div> | ||
| + | |group3 = [[Beta-lactam antibiotic|β-lactam]]s<br/>{{nobold|(inhibiting cross-links with [[Penicillin binding proteins|PBP]])}} | ||
| + | |list3 = | ||
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; line-height:1.2em; | ||
| + | |group1 = [[Penicillin]]s<br/>([[penam]]s) | ||
| + | |list1 = | ||
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; line-height:1.2em; | ||
| + | |group1 = [[Beta-lactam antibiotic#Extended-spectrum|Extended<br/>spectrum]] | ||
| + | |list1 = | ||
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; | ||
| + | |group1 = [[Aminopenicillin]]s | ||
| + | |list1 = <div> | ||
| + | [[Amoxicillin]]{{smallsup|1}} | ||
| + | </div> | ||
| + | |group2 = [[Ampicillin]]{{smallsup|1}} | ||
| + | |list2 = <div> | ||
| + | [[Pivampicillin]]{{·}} | ||
| + | [[Hetacillin]]{{·}} | ||
| + | [[Bacampicillin]]{{·}} | ||
| + | [[Metampicillin]]{{·}} | ||
| + | [[Talampicillin]]){{·}} | ||
| + | [[Epicillin]] | ||
| + | </div> | ||
| + | |group3 = [[Carboxypenicillin]]s | ||
| + | |list3 = <div> | ||
| + | [[Carbenicillin]] ([[Carindacillin]]){{·}} | ||
| + | [[Ticarcillin]]{{·}} | ||
| + | [[Temocillin]] | ||
| + | </div> | ||
| + | |group4 = [[Ureidopenicillin]]s | ||
| + | |list4 = <div> | ||
| + | [[Azlocillin]]{{·}} | ||
| + | [[Piperacillin]]{{·}} | ||
| + | [[Mezlocillin]] | ||
| + | </div> | ||
| + | |group5 = Others | ||
| + | |group5style = font-weight:normal; | ||
| + | |list5 = <div> | ||
| + | [[Mecillinam]] ([[Pivmecillinam]]){{·}} | ||
| + | [[Sulbenicillin]] | ||
| + | </div> | ||
| + | }} | ||
| + | |group2 = [[Beta-lactam antibiotic#Narrow-spectrum|Narrow<br/>spectrum]] | ||
| + | |list2 = | ||
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; line-height:1.2em; | ||
| + | |group1 = [[Beta-lactam antibiotic#Narrow-spectrum|β-lactamase<br/>sensitive]] | ||
| + | |list1 = | ||
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; line-height:1.0em; font-weight:normal; | ||
| + | |evenodd = swap | ||
| + | |group1 = [[Benzylpenicillin|Benzylpenicillin (G)]]{{smallsup|1}} | ||
| + | |list1 = <div> | ||
| + | [[Clometocillin]]{{·}} | ||
| + | [[Benzathine benzylpenicillin]]{{smallsup|1}}{{·}} | ||
| + | [[Procaine benzylpenicillin]]{{smallsup|1}}{{·}} | ||
| + | [[Azidocillin]]{{·}} | ||
| + | [[Penamecillin]] | ||
| + | </div> | ||
| + | |group2style = padding-top:0.5em; padding-bottom:0.5em; | ||
| + | |group2 = [[Phenoxymethylpenicillin|Phenoxymethyl-<br/>penicillin (V)]]{{smallsup|1}} | ||
| + | |list2 = <div> | ||
| + | [[Propicillin]]{{·}} | ||
| + | [[Benzathine phenoxymethylpenicillin]]{{·}} | ||
| + | [[Pheneticillin]] | ||
| + | </div> | ||
| + | }} | ||
| + | |group2style = padding-top:0.5em; padding-bottom:0.5em; | ||
| + | |group2 = [[Beta-lactam antibiotic#Narrow-spectrum|β-lactamase<br/>resistant]] | ||
| + | |list2 = <div> | ||
| + | [[Cloxacillin]]{{smallsup|1}} ([[Dicloxacillin]]{{·}} | ||
| + | [[Flucloxacillin]]){{·}} | ||
| + | [[Oxacillin]]{{·}} | ||
| + | [[Meticillin]]{{·}} | ||
| + | [[Nafcillin]] | ||
| + | </div> | ||
| + | }} | ||
| + | }} | ||
| − | | | + | |group2 = [[Penem]]s |
| − | + | |list2 = <div> | |
| − | + | [[Faropenem]] | |
| + | </div> | ||
| − | | | + | |group3 = [[Carbapenem]]s |
| − | + | |list3 = <div> | |
| − | + | [[Biapenem]]{{·}} | |
| + | [[Doripenem]]{{·}} | ||
| + | [[Ertapenem]]{{·}} | ||
| + | [[Imipenem]]{{·}} | ||
| + | [[Meropenem]]{{·}} | ||
| + | [[Panipenem]] | ||
| + | </div> | ||
| − | | group1 = [[ | + | |group4 = [[Cephalosporin]]s ([[cephem]]s)<br/>by generation |
| − | | list1 = | + | |list4 = |
| + | {{Navbox subgroup | ||
| + | |groupstyle = background:PowderBlue; line-height:1.2em; | ||
| + | |group1 = [[Cephalosporin#First generation|First]]<br/>{{nobold|([[Proteus mirabilis|P]][[Escherichia coli|Ec]][[Klebsiella pneumoniae|K]])}} | ||
| + | |list1 = <div> | ||
| + | [[Cefazolin]]{{smallsup|1}}{{·}} [[Cefacetrile]]{{·}} [[Cefadroxil]]{{·}} [[Cefalexin]]{{·}} [[Cefaloglycin]]{{·}} [[Cefalonium]]{{·}} [[Cefaloridine]]{{·}} [[Cefalotin]]{{·}} [[Cefapirin]]{{·}} [[Cefatrizine]]{{·}} [[Cefazedone]]{{·}} [[Cefazaflur]]{{·}} [[Cefradine]]{{·}} [[Cefroxadine]]{{·}} [[Ceftezole]] | ||
| + | </div> | ||
| + | |group2 = [[Cephalosporin#Second generation|Second]]<br/>{{nobold|([[Haemophilus influenzae|H]][[Enterobacter aerogenes|E]][[Neisseria|N]])}} | ||
| + | |list2 = <div> | ||
| + | [[Cefaclor]]{{·}} [[Cefamandole]]{{·}} [[Cefminox]]{{·}} [[Cefonicid]]{{·}} [[Ceforanide]]{{·}} [[Cefotiam]]{{·}} [[Cefprozil]]{{·}} [[Cefbuperazone]]{{·}} [[Cefuroxime]]{{·}} [[Cefuzonam]]{{·}} | ||
| + | [[cephamycin]] ([[Cefoxitin]]{{·}} [[Cefotetan]]{{·}} [[Cefmetazole]]){{·}} | ||
| + | [[carbacephem]] ([[Loracarbef]]) | ||
| + | </div> | ||
| + | |group3 = [[Cephalosporin#Third generation|Third]] | ||
| + | |list3 = <div> | ||
| + | [[Cefixime]]{{smallsup|1}}{{·}} [[Ceftazidime]]{{smallsup|1}}{{·}} [[Ceftriaxone]]{{smallsup|1}}{{·}} [[Cefcapene]]{{·}} [[Cefdaloxime]]{{·}} [[Cefdinir]]{{·}} [[Cefditoren]]{{·}} [[Cefetamet]]{{·}} [[Cefmenoxime]]{{·}} [[Cefodizime]]{{·}} [[Cefoperazone]]{{·}} [[Cefotaxime]]{{·}} [[Cefpimizole]]{{·}} [[Cefpiramide]]{{·}} [[Cefpodoxime]]{{·}} [[Cefsulodin]]{{·}} [[Cefteram]]{{·}} [[Ceftibuten]]{{·}} [[Ceftiolene]]{{·}} [[Ceftizoxime]]{{·}} | ||
| + | [[oxacephem]] ([[Flomoxef]]{{·}} [[Latamoxef]]{{smallsup|3}}) | ||
| + | </div> | ||
| + | |group4 = [[Cephalosporin#Fourth generation|Fourth]] | ||
| + | |list4 = <div> | ||
| + | [[Cefepime]]{{·}} [[Cefozopran]]{{·}} [[Cefpirome]]{{·}} [[Cefquinome]] | ||
| + | </div> | ||
| + | |group5 = [[Cephalosporin#Fifth generation|Fifth]] | ||
| + | |list5 = <div> | ||
| + | [[Ceftobiprole]] | ||
| + | </div> | ||
| + | |group6 = [[Veterinary medicine|Veterinary]] | ||
| + | |list6 = <div> | ||
| + | [[Ceftiofur]]{{·}} [[Cefquinome]]{{·}} [[Cefovecin]]{{smallsup|1}} | ||
| + | </div> | ||
| + | }} | ||
| − | + | |group5 = [[Monobactams]] | |
| + | |list5 = <div> | ||
| + | [[Aztreonam]]{{·}}[[Tigemonam]] | ||
| + | </div> | ||
| − | + | |group6 = [[Beta-lactamase inhibitor|β-lactamase inhibitor]]s | |
| + | |list6 = <div> | ||
| + | [[penam]] ([[Sulbactam]]{{·}} [[Tazobactam]]){{·}} | ||
| + | [[clavam]] ([[Clavulanic acid]]) | ||
| + | </div> | ||
| − | + | |group7 = Combinations | |
| − | + | |list7 = <div> | |
| − | | | + | [[Co-amoxiclav|Co-amoxiclav (Amoxicillin/clavulanic acid)]]{{smallsup|1}}{{·}} |
| − | | | + | [[Imipenem/cilastatin]]{{smallsup|1}}{{·}} |
| − | + | [[Ampicillin/sulbactam]] ([[Sultamicillin]]){{·}} | |
| − | + | [[Piperacillin/tazobactam]] | |
| − | + | </div> | |
| − | + | }} | |
| − | |||
| − | |||
| − | |||
| − | |||
| − | | | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| + | |group4 = Other | ||
| + | |list4 = <div> | ||
| + | [[polymyxin]]s/[[detergent]] ([[Colistin]]{{·}} [[Polymyxin B]]){{·}} | ||
| + | [[Depolarization|depolarizing]] ([[Daptomycin]]){{·}} | ||
| + | {{nowrap|[[Hydrolysis|hydrolyzing]] [[N-Acetylmuramic acid|NAM]]-[[N-Acetylglucosamine|NAG]] ([[Lysozyme]])}} | ||
| + | </div> | ||
| + | |belowstyle = padding-top:0.2em; | ||
| + | |below = {{smallsup|1}} [[List of World Health Organization Essential Medicines|WHO-EM]]{{·}} {{smallsup|2}} [[List of withdrawn drugs|Withdrawn]]{{·}} {{smallsup|3}} [[Clinical trial#Phase III|Clinical trial phase III]]{{·}} {{smallsup|4}} [[Clinical trial#Phase II|Did not reach clinical trial phase III]] | ||
}}<noinclude> | }}<noinclude> | ||