Template:Cholesterol and steroid metabolism enzymes

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Metabolism: lipid metabolism – ketones/cholesterol synthesis enzymes/steroid metabolism

Mevalonate pathway

To HMG-CoA	Acetyl-Coenzyme A acetyltransferase HMG-CoA synthase (regulated step)
Ketogenesis	HMG-CoA lyase 3-hydroxybutyrate dehydrogenase Thiophorase
To Mevalonic acid	HMG-CoA reductase
To DMAPP	Mevalonate kinase Phosphomevalonate kinase Pyrophosphomevalonate decarboxylase Isopentenyl-diphosphate delta isomerase
Geranyl-	Dimethylallyltranstransferase Geranyl pyrophosphate

To lanosterol	Farnesyl-diphosphate farnesyltransferase Squalene monooxygenase Lanosterol synthase
7-Dehydrocholesterol path	Lanosterol 14α-demethylase Sterol-C5-desaturase-like 7-Dehydrocholesterol reductase
Desmosterol path	24-dehydrocholesterol reductase

Steroidogenesis

To pregnenolone

Side-chain cleavage

To corticosteroids

aldosterone: 18-hydroxylase

To sex hormones

To androgens	17α-hydroxylase/17,20 lyase 3β dehydrogenase 17β dehydrogenase 5α reductase 1 2
To estrogens	Aromatase

Other/ungrouped

Steroid metabolism: sulfatase (Steroid sulfatase)
sulfotransferase (SULT1A1, SULT2A1)

Steroidogenic acute regulatory protein

Template:Metabolic navs

v t e Index of hormones
Description	Glands Hormones thyroid intermediates metabolism mineralocorticoids Physiology Development
Disease	Diabetes Congenital Neoplasms and cancer
Treatment	Procedures Drugs calcium balance corticosteroids oral hypoglycemics pituitary and hypothalamic thyroid

ru:Шаблон:Ферменты-участники метаболизма холестерина и стероидов

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