Template:Endogenous estradiol production rates and plasma estrogen levels

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Endogenous estradiol production rates and plasma estrogen levels

Group E2 (prod) E2 (levels) E1 (levels) Ratio
Pubertal girls
  Tanner stage I (childhood)
  Tanner stage II (ages 8–12)
  Tanner stage III (ages 10–13)
  Tanner stage IV (ages 11–14)
  Tanner stage V (ages 12–15)
    Follicular (days 1–14)
    Luteal (days 15–28)
 
ND
ND
ND
ND
 
ND
ND
 
9 (<9–20) pg/mL
15 (<9–30) pg/mL
27 (<9–60) pg/mL
55 (16–85) pg/mL
 
50 (30–100) pg/mL
130 (70–300) pg/mL
 
13 (<9–23) pg/mL
18 (10–37) pg/mL
26 (17–58) pg/mL
36 (23–69) pg/mL
 
44 (30–89) pg/mL
75 (39–160) pg/mL
 
ND
ND
ND
ND
 
ND
ND
Prepubertal boys ND 2–8 pg/mL ND ND
Premenopausal women
  Early follicular phase (days 1–4)
  Mid follicular phase (days 5–9)
  Late follicular phase (days 10–14)
  Luteal phase (days 15–28)
  Oral contraceptive (anovulatory)
 
30–100 µg/day
100–160 µg/day
320–640 µg/day
300 µg/day
ND
 
40–60 pg/mL
60–100 pg/mL
200–400 pg/mL
190 pg/mL
12–50 pg/mL
 
40–60 pg/mL
ND
170–200 pg/mL
100–150 pg/mL
ND
 
0.5–1
ND
1–2
1.5
ND
Postmenopausal women 18 µg/day 5–20 pg/mL 30–70 pg/mL 0.3–0.8
Pregnant women
  First trimester (weeks 1–12)
  Second trimester (weeks 13–26)
  Third trimester (weeks 27–40)
 
ND
ND
ND
 
1,000–5,000 pg/mL
5,000–15,000 pg/mL
10,000–40,000 pg/mL
 
ND
ND
ND
 
ND
ND
ND
Men 20–60 µg/day 27 (20–55) pg/mL 20–90 pg/mL 0.4–0.6
Notes: Mean levels are given as a single value and ranges are given after in parentheses. Sources: [1][2][3][4][5][6][7]
Template documentation

References

  1. Nichols KC, Schenkel L, Benson H (1984). "17 beta-estradiol for postmenopausal estrogen replacement therapy". Obstet Gynecol Surv. 39 (4): 230–45. PMID 6717863.
  2. Cynthia C. Chernecky; Barbara J. Berger (31 October 2012). Laboratory Tests and Diagnostic Procedures – E-Book. Elsevier Health Sciences. pp. 488–. ISBN 1-4557-4502-2.
  3. Powers MS, Schenkel L, Darley PE, Good WR, Balestra JC, Place VA (August 1985). "Pharmacokinetics and pharmacodynamics of transdermal dosage forms of 17 beta-estradiol: comparison with conventional oral estrogens used for hormone replacement". Am. J. Obstet. Gynecol. 152 (8): 1099–106. doi:10.1016/0002-9378(85)90569-1. PMID 2992279.
  4. Kenneth L. Becker (2001). Principles and Practice of Endocrinology and Metabolism. Lippincott Williams & Wilkins. pp. 889, 1059–1060, 2153. ISBN 978-0-7817-1750-2.
  5. Lalit Bajaj; Stephen Berman (1 January 2011). Berman's Pediatric Decision Making. Elsevier Health Sciences. pp. 160–. ISBN 0-323-05405-6.
  6. http://www.ilexmedical.com/files/PDF/Estradiol_ARC.pdf
  7. Kuhl H (2003). "Östrogene für den Mann?" [Estrogens for the man?]. Blickpunkt der Mann. 1 (3): 6–12. ISSN 1727-0669.