| Vice President | None (1963–1965) · Hubert Humphrey (1965–1969) | |
|---|---|---|
| Secretary of State | Dean Rusk (1963–1969) | |
| Secretary of the Treasury | ||
| Secretary of Defense | Robert McNamara (1963–1968) · Clark Clifford (1968–1969) | |
| Attorney General | ||
| Postmaster General | ||
| Secretary of the Interior | Stewart Udall (1963–1969) | |
| Secretary of the Agriculture | Orville Freeman (1963–1969) | |
| Secretary of Commerce | Luther H. Hodges (1963–1965) · John T. Connor (1965–1967) · Alexander Buel Trowbridge (1967–1968) · C. R. Smith (1968–1969) | |
| Secretary of Labor | W. Willard Wirtz (1963–1969) | |
| Secretary of Health, Education and Welfare | Anthony J. Celebrezze (1963–1965) · John William Gardner (1965–1968) · Wilbur Joseph Cohen (1968–1969) | |
| Secretary of Housing and Urban Development | Robert Clifton Weaver (1966–1968) · Robert Coldwell Wood (1969) | |
| Secretary of Transportation | Alan Stephenson Boyd (1967–1969) | |