File:Mitochondrial dynamics after PXA treatment.webm

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Mitochondrial_dynamics_after_PXA_treatment.webm(file size: 327 KB, MIME type: video/webm)

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Summary

Description
English: Fluorescent microscopy live cell imaging time lapse video of the mitochondrial fission and mitochondrial fusion dynamics of a MEF cell after treatment with the mycotoxin phomoxanthone A (PXA). The real time is displayed in the top right corner. The mitochondria were stained with a DsRed derivative that localises to the mitochondrial matrix. Fragmentation of the mitochondrial network structure is visible as early as about 1 min after treatment.
Date
Source Böhler et al. (2018)
Author Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B. (2018). "The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane". Cell Death & Disease 9 (3): e286. DOI:10.1038/s41419-018-0312-8.
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19 February 2018

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Date/TimeDimensionsUserComment
current12:00, 21 February 2018 (327 KB)Shinryuu{{Information |Description={{en|{{w|Fluorescent microscopy}} {{w|live cell imaging}} time lapse video of the {{w|mitochondrial fission}} and {{w|mitochondrial fusion}} dynamics of a {{w|Mouse embryonic fibroblast|MEF}} cell after treatment with the mycotoxin {{w|phomoxanthone A}} (PXA). The real time is displayed in the top right corner. The mitochondria were stained with a {{w|DsRed}} derivative that localises to the {{w|mitochondrial matrix}}. Fragmentation of the mitochondrial network structure is visible as early as about 1 min after treatment.}} |Source=[https://www.nature.com/articles/s41419-018-0312-8 Böhler et al. (2018)] |Date={{Date|2018|02|19}} |Author={{cite journal | authors = Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg...

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