Template:Did you know nominations/beta-Hydroxy beta-methylbutyric acid
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- The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.
The result was: promoted by Yoninah (talk) 00:38, 21 January 2018 (UTC)
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Beta-Hydroxy beta-methylbutyric acid

Structural formula of the free acid form of HMB
- ... that HMB (pictured) has been shown to prevent age-related muscle loss, increase exercise-induced gains in muscle size, muscle strength, and lean body mass, reduce muscle damage, and speed recovery from exercise?
Source: In the body of this article, the 5 effects listed after "age-related muscle loss" in this hook are cited by the 6 medical/systematic reviews or meta-analyses included in Special:permalink/817078326#cite_note-45; the effect on age-related muscle loss (i.e., sarcopenia) is cited by references [10] and [11] in the preceding note link (i.e., Template:PMID and Template:PMID) as well as Special:Permalink/817078326#cite_note-HMB_for_sarcopenia_and_sarcopenic_obesity_–_October_2017_review-13 (Template:PMID). All of the citations to those references in this article include a relevant quote in the citation's quote parameter; most of those quotes cover the effects listed here.- ALT1: ... that the dietary supplement HMB (pictured) has been shown to increase muscle mass and improve muscle strength in older adults with sarcopenia?
Source: See the references listed above for "age-related muscle loss"; for brevity, I'll just quote 1 review:
- ALT1: ... that the dietary supplement HMB (pictured) has been shown to increase muscle mass and improve muscle strength in older adults with sarcopenia?
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- ALT2: ... that, in healthy adults, HMB (pictured) has been shown to increase exercise-induced gains in muscle size, muscle strength, and lean body mass, reduce muscle damage, and speed recovery from exercise?
Source: See above; I'll just quote 2 reviews here:
- ALT2: ... that, in healthy adults, HMB (pictured) has been shown to increase exercise-induced gains in muscle size, muscle strength, and lean body mass, reduce muscle damage, and speed recovery from exercise?
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- Comment: While the acronym "HMB" might seem more ambiguous relative to using the article title, some of the reviews of clinical studies with this compound focus exclusively on either the conjugate acid (β-hydroxy β-methylbutyric acid) or the conjugate base (β-hydroxy β-methylbutyrate). "HMB" refers to both, every review uses the acronym "HMB", and both forms are commercially available.
Improved to Good Article status by Seppi333 (talk) and Boghog (talk). Nominated by Seppi333 (talk) at 00:39, 27 December 2017 (UTC).
- Comment: In my opinion the chemical structure is not picture-worthy. David notMD (talk) 04:46, 27 December 2017 (UTC)
GA, in time, long enough, sourced, inline hook citations check out (Template:U, thanks for the note under ALT0), no apparent copyvios, QPQ not needed (2nd DYK). Image is fine, although I agree with Template:U. Ho-o-oh coulda almost worked for Christmas, though... --Usernameunique (talk) 16:50, 27 December 2017 (UTC)