Template:Effects of feminizing hormone therapy in transgender women
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| Effect | Time to expected onset of effect[lower-alpha 1] |
Time to expected maximum effect[lower-alpha 1][lower-alpha 2] |
Permanency if hormone therapy is stopped |
|---|---|---|---|
| Breast development and nipple/areolar enlargement | 2–6 months | 1–3 years | Permanent |
| Thinning/slowed growth of facial/body hair | 4–12 months | >3 years[lower-alpha 3] | Reversible |
| Cessation/reversal of male-pattern scalp hair loss | 1–3 months | 1–2 years[lower-alpha 4] | Reversible |
| Softening of skin/decreased oiliness and acne | 3–6 months | Unknown | Reversible |
| Redistribution of body fat in a feminine pattern | 3–6 months | 2–5 years | Reversible |
| Decreased muscle mass/strength | 3–6 months | 1–2 years[lower-alpha 5] | Reversible |
| Widening and rounding of the pelvis[lower-alpha 6] | Unspecified | Unspecified | Permanent |
| Changes in mood, emotionality, and behavior | Unspecified | Unspecified | Reversible |
| Decreased sex drive | 1–3 months | 3–6 months | Reversible |
| Decreased spontaneous/morning erections | 1–3 months | 3–6 months | Reversible |
| Erectile dysfunction and decreased ejaculate volume | 1–3 months | Variable | Reversible |
| Decreased sperm production/fertility | Unknown | >3 years | Reversible or permanent[lower-alpha 7] |
| Decreased testicle size | 3–6 months | 2–3 years | Unknown |
| Decreased penis size | None[lower-alpha 8] | Not applicable | Not applicable |
| Decreased prostate gland size | Unspecified | Unspecified | Unspecified |
| Voice changes | None[lower-alpha 9] | Not applicable | Not applicable |
Footnotes and sources
Footnotes:
| |||
References
- ↑ Elliott S, Latini DM, Walker LM, Wassersug R, Robinson JW (September 2010). "Androgen deprivation therapy for prostate cancer: recommendations to improve patient and partner quality of life". J Sex Med. 7 (9): 2996–3010. doi:10.1111/j.1743-6109.2010.01902.x. PMID 20626600.
- ↑ Higano CS (February 2003). "Side effects of androgen deprivation therapy: monitoring and minimizing toxicity". Urology. 61 (2 Suppl 1): 32–8. doi:10.1016/S0090-4295(02)02397-X. PMID 12667885.
- ↑ Higano CS (October 2012). "Sexuality and intimacy after definitive treatment and subsequent androgen deprivation therapy for prostate cancer". J. Clin. Oncol. 30 (30): 3720–5. doi:10.1200/JCO.2012.41.8509. PMID 23008326.
- ↑ Eberhard Nieschlag; Hermann Behre (29 June 2013). Andrology: Male Reproductive Health and Dysfunction. Springer Science & Business Media. pp. 54–. ISBN 978-3-662-04491-9.
- ↑ Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, Rosenthal SM, Safer JD, Tangpricha V, T'Sjoen GG (November 2017). "Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline" (PDF). J. Clin. Endocrinol. Metab. 102 (11): 3869–3903. doi:10.1210/jc.2017-01658. PMID 28945902. S2CID 3726467.
- ↑ Coleman, E.; Bockting, W.; Botzer, M.; Cohen-Kettenis, P.; DeCuypere, G.; Feldman, J.; Fraser, L.; Green, J.; Knudson, G.; Meyer, W. J.; Monstrey, S.; Adler, R. K.; Brown, G. R.; Devor, A. H.; Ehrbar, R.; Ettner, R.; Eyler, E.; Garofalo, R.; Karasic, D. H.; Lev, A. I.; Mayer, G.; Meyer-Bahlburg, H.; Hall, B. P.; Pfaefflin, F.; Rachlin, K.; Robinson, B.; Schechter, L. S.; Tangpricha, V.; van Trotsenburg, M.; Vitale, A.; Winter, S.; Whittle, S.; Wylie, K. R.; Zucker, K. (2012). "Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7" (PDF). International Journal of Transgenderism. 13 (4): 165–232. doi:10.1080/15532739.2011.700873. ISSN 1553-2739. S2CID 39664779.
- ↑ Bourns, Amy (2015). "Guidelines and Protocols for Comprehensive Primary Care for Trans Clients" (PDF). Sherbourne Health Centre. Retrieved 15 August 2018.
- ↑ Wesp LM, Deutsch MB (March 2017). "Hormonal and Surgical Treatment Options for Transgender Women and Transfeminine Spectrum Persons". Psychiatr. Clin. North Am. 40 (1): 99–111. doi:10.1016/j.psc.2016.10.006. PMID 28159148.
- ↑ Fisher, Alessandra Daphne; Maggi, Mario (2015). "Endocrine Treatment of Transsexual Male-to-Female Persons". Management of Gender Dysphoria. pp. 83–91. doi:10.1007/978-88-470-5696-1_10. ISBN 978-88-470-5695-4.
- ↑ Fabris B, Bernardi S, Trombetta C (March 2015). "Cross-sex hormone therapy for gender dysphoria". J. Endocrinol. Invest. 38 (3): 269–82. doi:10.1007/s40618-014-0186-2. PMID 25403429. S2CID 207503049.
- ↑ Radix, Asa E. (2016). "Medical Transition for Transgender Individuals". Lesbian, Gay, Bisexual, and Transgender Healthcare. pp. 351–361. doi:10.1007/978-3-319-19752-4_19. ISBN 978-3-319-19751-7.
- ↑ Tangpricha V, den Heijer M (April 2017). "Oestrogen and anti-androgen therapy for transgender women". Lancet Diabetes Endocrinol. 5 (4): 291–300. doi:10.1016/S2213-8587(16)30319-9. PMC 5366074. PMID 27916515.
- ↑ Moore E, Wisniewski A, Dobs A (August 2003). "Endocrine treatment of transsexual people: a review of treatment regimens, outcomes, and adverse effects". The Journal of Clinical Endocrinology and Metabolism. 88 (8): 3467–73. doi:10.1210/jc.2002-021967. PMID 12915619.
- ↑ Asscheman, Henk; Gooren, Louis J.G. (1993). "Hormone Treatment in Transsexuals". Journal of Psychology & Human Sexuality. 5 (4): 39–54. doi:10.1300/J056v05n04_03. ISSN 0890-7064.
- ↑ Levy A, Crown A, Reid R (October 2003). "Endocrine intervention for transsexuals". Clin. Endocrinol. (Oxf). 59 (4): 409–18. doi:10.1046/j.1365-2265.2003.01821.x. PMID 14510900. S2CID 24493388.
- ↑ de, Blok Christel; Klaver, Maartje; Nota, Nienke; Dekker, Marieke; den, Heijer Martin (2016). "Breast development in male-to-female transgender patients after one year cross-sex hormonal treatment". Endocrine Abstracts. doi:10.1530/endoabs.41.GP146. ISSN 1479-6848.
- ↑ de Blok CJ, Klaver M, Wiepjes CM, Nota NM, Heijboer AC, Fisher AD, Schreiner T, T'Sjoen G, den Heijer M (February 2018). "Breast Development in Transwomen After 1 Year of Cross-Sex Hormone Therapy: Results of a Prospective Multicenter Study". J. Clin. Endocrinol. Metab. 103 (2): 532–538. doi:10.1210/jc.2017-01927. PMID 29165635. S2CID 3716975.
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