Template:Infobox drug/ELbox

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Infobox drug/ELbox
INN: acetylsalicylic acid
Aspirin-skeletal.svg
Aspirin-B-3D-balls.png
Clinical data
Pronunciationacetylsalicylic acid /əˌstəlˌsælɪˈsɪlɪk/
Other names2-acetoxybenzoic acid
acetylsalicylate
acetylsalicylic acid
O-acetylsalicylic acid, Aspirin (BAN UK), Aspirin (USAN US)
AHFS/Drugs.comMonograph
MedlinePlusa682878
License data
Pregnancy
category
  • AU: C
Routes of
administration
by mouth, rectal, lysine acetylsalicylate may be given intravenously or intramuscularly
ATC code
Legal status
Legal status
  • AU: S2 (Pharmacy medicine) except when given intravenously (in which case it is schedule 4), used in animal medicine (schedule 5/6) or when the dose is higher than usual.
  • UK: General sales list (GSL, OTC)
  • US: OTC
Pharmacokinetic data
Bioavailability80–100%[1]
Protein binding80–90%[2]
MetabolismLiver, (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.[2]
Elimination half-lifeDose-dependent; 2 h to 3 h for low doses, 15 h to 30 h for large doses.[2]
ExcretionUrine (80–100%), sweat, saliva, feces[1]
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
PDB ligand
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC9H8O4
Molar mass180.157 g/mol g·mol−1
3D model (JSmol)
Density1.40 g/cm3
Melting point135 °C (275 °F)
Boiling point140 °C (284 °F) (decomposes)
Solubility in water3 mg/mL (20 °C)
  (verify)
  1. 1.0 1.1 "Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 7 April 2014. Retrieved 3 April 2014.
  2. 2.0 2.1 2.2 Brayfield, A, ed. (14 January 2014). "Aspirin". Martindale: The Complete Drug Reference. Pharmaceutical Press. Retrieved 3 April 2014.