Template:Infobox drug/ELbox
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| Clinical data | |
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| Pronunciation | acetylsalicylic acid /əˌsiːtəlˌsælɪˈsɪlɪk/ |
| Other names | 2-acetoxybenzoic acid acetylsalicylate acetylsalicylic acid O-acetylsalicylic acid, Aspirin (BAN UK), Aspirin (USAN US) |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682878 |
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| Routes of administration | by mouth, rectal, lysine acetylsalicylate may be given intravenously or intramuscularly |
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| Pharmacokinetic data | |
| Bioavailability | 80–100%[1] |
| Protein binding | 80–90%[2] |
| Metabolism | Liver, (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.[2] |
| Elimination half-life | Dose-dependent; 2 h to 3 h for low doses, 15 h to 30 h for large doses.[2] |
| Excretion | Urine (80–100%), sweat, saliva, feces[1] |
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| E number | {{#property:P628}} |
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| ECHA InfoCard | {{#property:P2566}}Script error: No such module "EditAtWikidata". |
| Chemical and physical data | |
| Formula | C9H8O4 |
| Molar mass | 180.157 g/mol g·mol−1 |
| 3D model (JSmol) | |
| Density | 1.40 g/cm3 |
| Melting point | 135 °C (275 °F) |
| Boiling point | 140 °C (284 °F) (decomposes) |
| Solubility in water | 3 mg/mL (20 °C) |
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- ↑ 1.0 1.1 "Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 7 April 2014. Retrieved 3 April 2014.
- ↑ 2.0 2.1 2.2 Brayfield, A, ed. (14 January 2014). "Aspirin". Martindale: The Complete Drug Reference. Pharmaceutical Press. Retrieved 3 April 2014.